Evidence map›Paper›PMID 28536755›Full record

ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2018

Taurine protects cardiac contractility in killifish, Fundulus heteroclitus, by enhancing sarcoplasmic reticular Ca

Elenor F Henry, Tyson J MacCormack

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Taurine in canine physiology and metabolic regulation.Frontiers in veterinary science · 2026
    Review
  2. Review
  3. Article
  4. Intracellular taurine deficiency impairs cardiac contractility in rainbow trout (Oncorhynchus mykiss) without affecting aerobic performance.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022
    Article
  5. Review
  6. Taurine administration ablates sepsis induced diaphragm weakness.Respiratory physiology & neurobiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elenor F HenryDepartment of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L1G8, Canada.
Tyson J MacCormackDepartment of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L1G8, Canada. tmaccormack@mta.ca.ORCID 0000-0002-6080-9413
Mount Allison University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular taurine is abundant in many animals and it influences an array of physiological processes, including osmoregulation, metabolism, and cardiac contractility. Taurine is an important osmolyte in teleost hearts, but its role in stress tolerance, cardiac metabolism, and contractility has not been assessed. The goal of this study was to determine if ventricular taurine concentration changes in response to environmental stress and to characterize its influence on contractility. Cardiac taurine concentrations varied in killifish (Fundulus heteroclitus) but were generally maintained following acute environmental challenges. In isometrically contracting ventricular strips, supplemental taurine (40 mmol L

Indexed as

AnimalsCalciumCardiotonic AgentsFemaleFundulidaeHypoxiaMaleMyocardial ContractionMyocardiumRyanodineSarcoplasmic ReticulumTaurineVentricular FunctionCalciumCardiotonic AgentsRyanodineTaurineAnoxiaCalcium sensitivityFish heartGlucose metabolismKillifishReoxygenationRyanodineTaurine

Identifiers

PMID28536755
OpenAlexW2619501332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.