Evidence map›Paper›PMID 28536616›Full record

ArticleCellular & molecular biology letters2016

Effects of NH

Miha Bartolić, Andrej Vovk, Dušan Šuput

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular & molecular biology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04131205 (Role of Magnetic Resonance Imaging in Detection of Minimal Hepatic Encephalopathy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04131205 unknown statusnot on this mapstarted 2019, after this paper: background citation

Role of Magnetic Resonance Imaging in Detection of Minimal Hepatic Encephalopathy

TypeobservationalSponsorUniversity Medical Centre LjubljanaRan2019 to 2023Enrolled40ConditionsLiver Cirrhoses, Hepatic EncephalopathyArmsMagnetic Resonance Imaging
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Miha BartolićInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloška cesta 4, 1000 Ljubljana, Slovenia.
Andrej VovkInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloška cesta 4, 1000 Ljubljana, Slovenia.
Dušan ŠuputInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloška cesta 4, 1000 Ljubljana, Slovenia.
University of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatic encephalopathy (HE) is a complex disorder associated with increased ammonia levels in the brain. Although astrocytes are believed to be the principal cells affected in hyperammonemia (HA), endothelial cells (ECs) may also play an important role by contributing to the vasogenic effect of HA.

methodsFollowing acute application and removal of NH

resultsExposure of astrocytes and ECs to 1 - 20 mM NH

conclusionsThis study reveals new data which may give a more complete insight into the mechanism of development and treatment of HE.

Indexed as

Ammonium HydroxideAnimalsAstrocytesCalciumCells, CulturedEndothelial CellsHepatic EncephalopathyHumansHydrogen-Ion ConcentrationHyperammonemiaKineticsRatsAmmonium HydroxideCalciumAmmoniaAstrocytesCalciumEndothelial cellsHepatic encephalopathyHyperammonemiapHVolume

Identifiers

PMID28536616
PMCPMC5414667
OpenAlexW2514689964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.