Evidence map›Paper›PMID 28536575›Full record

ArticleFrontiers in immunology2017

Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers.

Sofia Pavanello, Mariarita Stendardo, Giuseppe Mastrangelo, Melissa Bonci, Barbara Bottazzi, Manuela Campisi, Marco Nardini, Roberto Leone, Alberto Mantovani, Piera Boschetto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Review
  6. Impact of night shift work on telomere length and epigenetic age in older workers.Journal of occupational medicine and toxicology (London, England) · 2025
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  7. Review
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  11. The effect of high polycyclic aromatic hydrocarbon exposure on biological aging indicators.Environmental health : a global access science source · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sofia PavanelloOccupational Medicine, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
Mariarita StendardoDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Giuseppe MastrangeloOccupational Medicine, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
Melissa BonciDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Barbara BottazziLaboratory of Research in Immunology and Inflammation, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Manuela CampisiOccupational Medicine, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
Marco NardiniDepartment of Prevention and Protection, University-Hospital and Public Health Service of Ferrara, Ferrara, Italy.
Roberto LeoneLaboratory of Research in Immunology and Inflammation, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Alberto MantovaniLaboratory of Research in Immunology and Inflammation, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Piera BoschettoDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
University of Ferrara · ITHumanitas University · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is an emerging worldwide threat to public health, even in the workplace, as it links with risk of illness and death. Bewildered inflammatory responses and stressful conditions associate with age-related disorders. Additionally, circadian rhythm disruption, a critical health issue in night-shift workers, correlates with premature aging. We investigated the hypothesis of a link between altered inflammatory response, detected by plasmatic long pentraxin 3 (PTX3), and biological aging, measured by leukocyte telomere length (LTL), attrition, and possibly induced by night-shift work. Within the framework of a cross-sectional study, such possible relationships were appraised by simultaneous equation model (SEM) technique among day and night-shift hospital workers. PTX3 levels, modulated by several aging conditions [i.e., body mass index (BMI) (beta = -0.22;

Indexed as

agingcircadian rhythmgenetic instabilityinflammationnight-shift workpentraxin 3prematuretelomere

Identifiers

PMID28536575
PMCPMC5422482
OpenAlexW2613294905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.