ArticleScientific reports2017
Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea).
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 95 citations in OpenAlex.
- Dietary fish oil-corn oil balance modulates growth and metabolic homeostasis of Acrossocheilus fasciatus (Steindachner, 1892) under chronic heat stress.Fish physiology and biochemistry · 2026Article
- Fetuin-b Mediates Lipid Overload-Induced Hepatic Lipid Accumulation in Large Yellow Croaker (Larimichthys crocea).FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- A novel RELA K119 deacetylation mediated by SIRT7 is a pivotal activator to exacerbate liver inflammation and fibrosis in teleosts.Marine life science & technology · 2025Article
- Physiological Effects of Water Salinity on Metabolism and Fatty Acid Biosynthesis in the Model FishAnimals : an open access journal from MDPI · 2025Article
- Molecular Identification and Functional Characterization of LC-PUFA Biosynthesis Elongase (Animals : an open access journal from MDPI · 2024Article
- Contribution ofAnimals : an open access journal from MDPI · 2024Article
- FTO Regulates Apoptosis in CPB2-Treated IPEC-J2 Cells by Targeting Caspase 3 Apoptotic Protein.Animals : an open access journal from MDPI · 2022Article
- Regulation of Δ6Fads2 Gene Involved in LC-PUFA Biosynthesis Subjected to Fatty Acid in Large Yellow Croaker (Biomolecules · 2022Article
- FXR, a Key Regulator of Lipid Metabolism, Is Inhibited by ER Stress-Mediated Activation of JNK and p38 MAPK in Large Yellow Croakers (Nutrients · 2021Article
- High Fat Activates O-GlcNAcylation and Affects AMPK/ACC Pathway to Regulate Lipid Metabolism.Nutrients · 2021Article
- Effects of High Levels of Dietary Linseed Oil on the Growth Performance, Antioxidant Capacity, Hepatic Lipid Metabolism, and Expression of Inflammatory Genes in Large Yellow Croaker (Frontiers in physiology · 2021Article
- The requirements for sterol regulatory element-binding protein (Srebp) and stimulatory protein 1 (Sp1)-binding elements in the transcriptional activation of two freshwater fish Channa striata and Danio rerio elovl5 elongase.Fish physiology and biochemistry · 2020Article
- Molecular and Functional Characterization ofInternational journal of molecular sciences · 2020Article
- Molecular Characterization, Nutritional and Insulin Regulation of Elovl6 in Rainbow Trout (Biomolecules · 2020Article
- Molecular Cloning, Characterization, and Nutritional Regulation of Elovl6 in Large Yellow Croaker (International journal of molecular sciences · 2019Article
- Elovl4a participates in LC-PUFA biosynthesis and is regulated by PPARαβ in golden pompano Trachinotus ovatus (Linnaeus 1758).Scientific reports · 2019Article
- The elongation of very long-chain fatty acid 6 gene product catalyses elongation ofThe British journal of nutrition · 2019Article
- TIR Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Participates in Antiviral Immune Responses and Hepatic Lipogenesis of Large Yellow Croaker (Frontiers in immunology · 2019Article
- Identification of Fatty Acid Desaturase 6 in Golden PompanoInternational journal of molecular sciences · 2018Article
- Hnf4α Is Involved in LC-PUFA Biosynthesis by Up-Regulating Gene Transcription of Elongase in Marine TeleostInternational journal of molecular sciences · 2018Article
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, two elongases, Elovl4 and Elovl5, were functionally characterized and their transcriptional regulation in response to n-3 LC-PUFA administration were investigated in vivo and in vitro. We previously described the molecular characterization of croaker elovl5. Here, we report the full-length cDNA sequence of croaker elovl4, which contained 1794 bp (excluding the polyA tail), including 909 bp of coding region that encoded a polypeptide of 302 amino acids possessing all the characteristic features of Elovl proteins. Functional studies showed that croaker Elovl5, displayed high elongation activity towards C
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