ReviewBiomedicines2017
Update on Treatment Guideline in Fibromyalgia Syndrome with Focus on Pharmacology.
Review in Biomedicines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Intermittent Theta Burst Stimulation to the Primary Motor Cortex on Pain Intensity, Pain Catastrophizing, Quality of Life and Mood in Fibromyalgia Patients
Evaluation of the Effect of Curcumin and Piperine Supplementation on Clinical Outcome in Fibromyalgia Patients.
Who cites it
55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 147 citations in OpenAlex.
- Peripheral magnetic stimulation for the treatment of fibromyalgia: a systematic review and meta-analysis.Pain management · 2025Pooled it
- Duloxetine for fibromyalgia syndrome: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Placebo Responses and Their Clinical Implications in Fibromyalgia: A Meta-Analysis Using SSRI and SNRI Trials.Frontiers in pain research (Lausanne, Switzerland) · 2021Pooled it
- Psychotherapy for Physical Pain in Patients with Fibromyalgia: A Systematic Review.Pain research & management · 2020Pooled it
- The role of mirtazapine in patients with fibromyalgia: a systematic review.Rheumatology international · 2018Pooled it
- No effect of approved fibromyalgia drugs on the social pain (invalidation) contrary to physical pain: an open-label short-term randomized clinical trial.Clinical rheumatology · 2022Trial
- Trial
- Comparing duloxetine and pregabalin for treatment of pain and depression in women with fibromyalgia: an open-label randomized clinical trial.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019Trial
- Short-term effects of pilates and aerobic exercise on cognitive functions and biochemical factors in women with fibromyalgia: a randomized controlled trial.Clinical rheumatology · 2026Article
- Non-Invasive Brain Stimulation for Core Symptoms of Chronic Primary Pain: A Meta-Analysis of RCTs.Brain sciences · 2026Review
- Cost-Effectiveness of Pregabalin, Duloxetine, and Milnacipran vs Amitriptyline for Moderate to Severe Fibromyalgia.JAMA network open · 2026Article
- Chronic Pain and Newly Reported Frequent Feelings of Depression: A Nationally Representative Longitudinal Study in 2019-2020.Journal of pain research · 2026Article
- Article
- Disparities in diagnosis and management of chronic overlapping pain conditions in an observational study of medicare beneficiaries.The journal of pain · 2025Observational
- Scopoletin Attenuates Reserpine-Induced Pain-Depression Dyad in Mice via Modulation of Inflammation, Oxidative Stress, and Monoaminergic Pathways.Neuromolecular medicine · 2025Article
- Novel Trajectories Towards Possible Effects of Semaglutide for Amelioration of Reserpine-induced Fibromyalgia in Rats: Contribution of cAMP/PKA/p-CREB and M1/M2 Microglia Polarization.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025Article
- Spinal manipulation for fibromyalgia: a narrative review.The Journal of the Canadian Chiropractic Association · 2025Article
- Cannabis: an opioid alternative for pain management in rheumatic diseases?Proceedings (Baylor University. Medical Center) · 2025Article
- Repetitive Transcranial Magnetic Stimulation in Fibromyalgia: Exploring the Necessity of Neuronavigation for Targeting New Brain Regions.Journal of personalized medicine · 2024Review
- Management of Fibromyalgia: An Update.Biomedicines · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibromyalgia syndrome (FMS) is a chronic condition with unknown aetiology. The pathophysiology of the disease is incompletely understood; despite advances in our knowledge with regards to abnormal central and peripheral pain processing, and hypothalamo-pituitary-adrenal dysfunction, there is no clear specific pathophysiological therapeutic target. The management of this complex condition has thus perplexed the medical community for many years, and several national and international guidelines have aimed to address this complexity. The most recent guidelines from European League Against Rheumatism (EULAR) (2016), Canadian Pain Society (2012), and The Association of the Scientific Medical Societies in Germany (AWMF) (2012) highlight the change in attitudes regarding the overall approach to FMS, but offer varying advice with regards to the use of pharmacological agents. Amitriptyline, Pregabalin and Duloxetine are used most commonly in FMS and though modestly effective, are useful adjunctive treatment to non-pharmaceutical measures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.