ArticleThe Journal of biological chemistry2017
Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy.
Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Development of a Novel Compound Effective Against Juvenile, Adult, and Drug-ResistantPharmaceutics · 2025Review
- Structural Mechanisms Driving the Selective Efficacy of Oxamniquine against Schistosoma mansoni and Schistosoma japonicum.Cell biochemistry and biophysics · 2025Article
- Detoxome Capacity of the Adult Rumen FlukeJournal of proteome research · 2025Article
- Review
- Schistosomiasis.Advances in experimental medicine and biology · 2024Review
- Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.PLoS pathogens · 2023Article
- Schistosome Sulfotransferases: Mode of Action, Expression and Localization.Pharmaceutics · 2022Article
- Clustered Regularly Interspaced Short Palindromic Repeats/ CRISPR associated protein 9-mediated editing of Schistosoma mansoni genes: Identifying genes for immunologically potent drug and vaccine development.Revista da Sociedade Brasileira de Medicina Tropical · 2022Review
- Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vectorCurrent research in structural biology · 2022Article
- An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.PLoS neglected tropical diseases · 2020Article
- Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?International journal for parasitology. Drugs and drug resistance · 2020Article
- Schistosomiasis then and now: what has changed in the last 100 years?Parasitology · 2020Review
- Molecular basis for hycanthone drug action in schistosome parasites.Molecular and biochemical parasitology · 2020Article
- Whole genome amplification and exome sequencing of archived schistosome miracidia.Parasitology · 2018Article
- Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.ACS medicinal chemistry letters · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
Abstract
The antischistosomal prodrug oxamniquine is activated by a sulfotransferase (SULT) in the parasitic flatworm
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.