Evidence map›Paper›PMID 28536154›Full record

ArticleJournal of the American Heart Association2017

Gastric Bypass Surgery Produces a Durable Reduction in Cardiovascular Disease Risk Factors and Reduces the Long-Term Risks of Congestive Heart Failure.

Peter N Benotti, G Craig Wood, David J Carey, Vishal C Mehra, Tooraj Mirshahi, Michelle R Lent, Anthony T Petrick, Christopher Still, Glenn S Gerhard, Annemarie G Hirsch

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it, 132 citations in OpenAlex.

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  15. Association of psychiatric history with hypertension among adults who present for metabolic and bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2025
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Peter N BenottiGeisinger Obesity Institute, Geisinger Medical Center, Danville, PA pbenotti64@gmail.com.
G Craig WoodGeisinger Obesity Institute, Geisinger Medical Center, Danville, PA.
David J CareyCenter for Health Research, Geisinger Medical Center, Danville, PA.
Vishal C MehraGeisinger Medical Center, Danville, PA.
Tooraj MirshahiCenter for Health Research, Geisinger Medical Center, Danville, PA.
Michelle R LentGeisinger Obesity Institute, Geisinger Medical Center, Danville, PA.
Anthony T PetrickGeisinger Medical Center, Danville, PA.
Christopher StillGeisinger Obesity Institute, Geisinger Medical Center, Danville, PA.
Glenn S GerhardTemple University, Philadelphia, PA.
Annemarie G HirschCenter for Health Research, Geisinger Medical Center, Danville, PA.
Geisinger Medical Center · USTemple College · US

Funding

Genetic Determinants of Weight Loss and Resolution of Co-MorbiditiesR01DK088231 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI GERHARD, GLENN S · 2011 to 2015
$2.5M
NIDDK NIH HHS R01 DK088231
6 · The paper itself

Abstract

backgroundObesity and its association with reduced life expectancy are well established, with cardiovascular disease as one of the major causes of fatality. Metabolic surgery is a powerful intervention for severe obesity, resulting in improvement in comorbid diseases and in cardiovascular risk factors. This study investigates the relationship between metabolic surgery and long-term cardiovascular events. METHODS AND

resultsA cohort of Roux-en-Y gastric bypass surgery (RYGB) patients was tightly matched by age, body mass index, sex, Framingham Risk Score, smoking history, use of antihypertension medication, diabetes mellitus status, and calendar year with a concurrent cohort of nonoperated control patients. The primary study end points of major cardiovascular events (myocardial infarction, stroke, and congestive heart failure) were evaluated using Cox regression. Secondary end points of longitudinal cardiovascular risk factors were evaluated using repeated-measures regression. The RYGB and matched controls (N=1724 in each cohort) were followed for up to 12 years after surgery (overall median of 6.3 years). Kaplan-Meier analysis revealed a statistically significant reduction in incident major composite cardiovascular events (

conclusionsGastric bypass is associated with a reduced risk of major cardiovascular events and the development of congestive heart failure.

Indexed as

ForecastingGastric BypassAdolescentAdultAgedAged, 80 and overBody Mass IndexCardiovascular DiseasesFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedObesity, MorbidRetrospective Studiesblood vesselcardiovascular eventscoronary artery diseaseendotheliumheart failuremetabolic syndromestroke

Identifiers

PMID28536154
PMCPMC5524077
OpenAlexW2619025168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.