ArticleDevelopment and psychopathology2018
Externalizing behavior severity in youths with callous-unemotional traits corresponds to patterns of amygdala activity and connectivity during judgments of causing fear.
Article in Development and psychopathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Associations between amygdala connectivity and experienced discrimination in children.bioRxiv : the preprint server for biology · 2026Article
- Alterations in Region-Specific Gray Matter Volume Underlying Callous Unemotional Traits in Adolescents.Brain and behavior · 2025Article
- Independent Impacts of Maltreatment and Amygdala Volume on Worsening Callous-Unemotional Traits in High-Risk Youths.Research on child and adolescent psychopathology · 2025Article
- The impact of adolescent clinical depression and depressive symptoms on moral thinking: based on process dissociation approach.Frontiers in psychology · 2025Article
- Adolescents in Treatment for Substance Use Disorders: Callous-Unemotional Traits Moderate Associations Between Transdiagnostic Symptoms and Adolescent Suicidality.Child psychiatry and human development · 2023Article
- Effect of subclinical depression on moral judgment dilemmas: a process dissociation approach.Scientific reports · 2022Article
- Are Children High on Callous-Unemotional Traits Emotionally Blind? Testing Eye-Gaze Differences.Child psychiatry and human development · 2022Article
- Bilateral amygdala damage linked to impaired ability to predict others' fear but preserved moral judgements about causing others fear.Proceedings. Biological sciences · 2021Article
- Clarifying the Link Between Amygdala Functioning During Emotion Processing and Antisocial Behaviors Versus Callous-Unemotional Traits Within a Population-Based Community Sample.Clinical psychological science : a journal of the Association for Psychological Science · 2020Article
- Is Callous Always Cold? A Critical Review of the Literature on Emotion and the Development of Callous-Unemotional Traits in Children.Clinical child and family psychology review · 2020Review
- Reduced Amygdala-Prefrontal Functional Connectivity in Children With Autism Spectrum Disorder and Co-occurring Disruptive Behavior.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019Article
- Anger provocation increases limbic and decreases medial prefrontal cortex connectivity with the left amygdala in reactive aggressive violent offenders.Brain imaging and behavior · 2019Article
- Inhibitory control and emotion dysregulation: A framework for research on anxiety.Development and psychopathology · 2019Article
- Callous and uncaring traits are associated with reductions in amygdala volume among youths with varying levels of conduct problems.Psychological medicine · 2019Article
- The Impact of Callous-Unemotional Traits and Externalizing Tendencies on Neural Responsivity to Reward and Punishment in Healthy Adolescents.Frontiers in neuroscience · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
Callous-unemotional (CU) traits characterize a subgroup of youths with conduct problems who exhibit low empathy, fearlessness, and elevated externalizing behaviors. The current study examines the role of aberrant amygdala activity and functional connectivity during a socioemotional judgment task in youths with CU traits, and links these deficits to externalizing behaviors. Functional magnetic resonance imaging was used to compare neural responses in 18 healthy youths and 30 youths with conduct problems and varying levels of CU traits as they evaluated the acceptability of causing another person to experience each of several emotions, including fear. Neuroimaging analyses examined blood oxygenation level dependent responses and task-dependent functional connectivity. High-CU youths exhibited left amygdala hypoactivation relative to healthy controls and low-CU youths primarily during evaluations of causing others fear. CU traits moderated the relationship between externalizing behavior and both amygdala activity and patterns of functional connectivity. The present data suggest that CU youths' aberrant amygdala activity and connectivity affect how they make judgments about the acceptability of causing others emotional distress, and that these aberrations represent risk factors for externalizing behaviors like rule breaking and aggression. These findings suggest that reducing externalizing behaviors in high-CU youths may require interventions that influence affective sensitivity.
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