Evidence map›Paper›PMID 28535666›Full record

ArticleMolecules and cells2017

DDX53 Regulates Cancer Stem Cell-Like Properties by Binding to SOX-2.

Youngmi Kim, Minjeong Yeon, Dooil Jeoung

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Genetic variants inmedRxiv : the preprint server for health sciences · 2023
    Article
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  12. Article
  13. Expression dynamics ofOncotarget · 2019
    Article
  14. Article
  15. Role of HDAC3-miRNA-CAGE Network in Anti-Cancer Drug-Resistance.International journal of molecular sciences · 2018
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Youngmi KimDepartment of Biochemistry, Kangwon National University, Chunchon 24341, Korea.
Minjeong YeonDepartment of Biochemistry, Kangwon National University, Chunchon 24341, Korea.
Dooil JeoungDepartment of Biochemistry, Kangwon National University, Chunchon 24341, Korea.
Kangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the role of cancer/testis antigen DDX53 in regulating cancer stem cell-like properties. DDX53 shows co-expression with CD133, a marker for cancer stem cells. DDX53 directly regulates the SOX-2 expression in anticancer drug-resistant Malme3M

Indexed as

AC133 AntigenAnimalsAntineoplastic Agents, PhytogenicCell Line, TumorDEAD-box RNA HelicasesDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticHumansMelanomaMice, Inbred BALB CMicroRNAsNeoplastic Stem CellsPaclitaxelSOXB1 Transcription FactorsXenograft Model Antitumor AssaysAC133 AntigenAntineoplastic Agents, PhytogenicDDX53 protein, humanDEAD-box RNA HelicasesMicroRNAsMIRN200 microRNA, humanPaclitaxelPROM1 protein, humanSOX2 protein, humanSOXB1 Transcription Factorsanti-cancer drug-resistancecancer stem cell-like propertiesDDX53SOX-2

Identifiers

PMID28535666
PMCPMC5463040
OpenAlexW2732292771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.