ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
Quality of life, anxiety and depression in patients with HIV/AIDS who present poor adherence to antiretroviral therapy: a cross-sectional study in Salvador, Brazil.
Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Pooled it
- The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis.AIDS research and therapy · 2021Pooled it
- Evaluating the relationship between adherence to antiretroviral therapy and health-related quality of life among people living with HIV/AIDS in Northwestern Nigeria.BMC public health · 2026Article
- The Relationships Between Internalized Stigma, Depression, andHealth-Related Quality of Life in Individuals Living with HIV.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2026Article
- Community violence in the HIV risk environment: a qualitative study among youth in Brazil.Cadernos de saude publica · 2026Article
- The effect of depression on antiretroviral drug non-adherence among women living with HIV in Gondar health facilities, northwest Ethiopia: a prospective cohort study.Frontiers in psychiatry · 2025Article
- Pathways to Poor Adherence to Antiretroviral Therapy Among People Living with HIV: The Role of Food Insecurity and Alcohol Misuse.AIDS and behavior · 2024Article
- Burden and predictors of anxiety disorder among HIV patients on ART in Nairobi Kenya.PLOS mental health · 2024Article
- The prevalence and determinants of social anxiety disorder among people living with HIV/AIDS in Southwestern Ethiopia: a cross-sectional study.Frontiers in psychiatry · 2024Article
- Patient experiences with value-based healthcare interventions at the HIV outpatient clinic of the Erasmus Medical Centre.PloS one · 2024Article
- Tools for Screening and Measuring Anxiety Among Women Living with HIV of Reproductive Age: A Scoping Review.AIDS and behavior · 2023Article
- Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study.Health and quality of life outcomes · 2023Article
- Prevalence, severity, and associated factors of depression in newly diagnosed people living with HIV in Kilimanjaro, Tanzania: a cross-sectional study.BMC psychiatry · 2023Article
- Exploring core mental health symptoms among persons living with HIV: A network analysis.Frontiers in psychiatry · 2023Article
- Depression symptoms, HIV testing, linkage to ART, and viral suppression among women in a high HIV burden district in KwaZulu-Natal, South Africa: A cross-sectional household study.Journal of health psychology · 2022Article
- Low Quality of Life, Falls, and Pre-Frailty are Associated with Depressive Symptoms in Virologically Suppressed PLWHIV in Salvador, Brazil.AIDS and behavior · 2022Article
- Prevalence of depressive symptoms in patients with rheumatoid arthritis at a regional hospital in KwaZulu-Natal, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2022Article
- Quality of Life Assessment and Related Factors of HIV-Infected Patients in Hangzhou Using a Path Analysis Model: An Observational Study.International journal of general medicine · 2022Article
- The role of personality, social economic and prevention strategy effects on health-related quality of life among people living with HIV/AIDS.Infectious diseases of poverty · 2021Article
- Does Posttraumatic Growth Buffer the Association Between Death Anxiety and Quality of Life Among People living with HIV/AIDS?Journal of clinical psychology in medical settings · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The introduction of highly active antiretroviral therapy marked a major gain in efficacy of HIV/AIDS treatment and a reduction in morbidity and mortality of the infected patients. However, high levels of adherence are required to obtain virologic suppression. In Brazil, the policy of free and universal access to antiretroviral therapy has been in place since 1996, although there are reports of poor adherence.
objectiveTo define the clinical, demographic and psychological characteristics, and quality of life of patients with HIV/AIDS who present poor adherence to highly active antiretroviral therapy.
methodsThis was a cross-sectional study. To be included in the study patients had to be 18 through 65 years old, diagnosed with HIV/AIDS, having the two previous viral loads above 500 copies, a surrogate for poor adherence to antiretrovirals. The following instruments were applied to all eligible patients: the sociodemographic questionnaire "Adherence Follow-up Questionnaire", the Beck Depression Inventory (BDI-II), the Beck Anxiety Inventory (BAI), and the 36-Item Short Form Survey.
results47 patients were evaluated, 70.2% were female, mean age of 41.9 years (±10.5), 46.8% were single, 51.1% self-reported adherence ≥95%, 46.8% mentioned depression as the main reason for not taking the medication, 59.5% presented symptoms of moderate to severe depression, and 44.7% presented symptoms of moderate to severe anxiety. Finally, regarding health-related quality of life these patients obtained low scores in all dimensions, physical component summary of 43.96 (±9.64) and mental component summary of 33.19 (±13.35).
conclusionThe psychological component is considered to be fundamental in the management of HIV/AIDS patients. Psychoeducation should be conducted at the initial evaluation to reduce negative beliefs regarding antiretroviral therapy Assessment of anxiety and depression symptoms should be done throughout therapy as both psycological conditions are associated with patient adherence, success of treatment, and ultimately with patients' quality of life.
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