ArticleJournal of the American Chemical Society2017
Cancer Cell Discrimination Using Host-Guest "Doubled" Arrays.
Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Nanozyme Aptasensor Array for Predictive Sensing of Virulent and Antibiotic-Resistant Staphylococcus Aureus strains.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Review
- The Rise and Promise of Macrocyclic Hosts in Biomedicine.ACS central science · 2025Review
- Development of Optical Differential Sensing Based on Nanomaterials for Biological Analysis.Biosensors · 2024Review
- Synthetic Receptors for Early Detection and Treatment of Cancer.Biosensors · 2023Review
- A Multichannel Fluorescent Array Sensor for Discrimination of Different Types of Drug-Induced Kidney Injury.Sensors (Basel, Switzerland) · 2023Article
- Rapid detection of carbamate nerve agent analogues using dually functionalized gold nanoclusters.Analytical and bioanalytical chemistry · 2023Article
- Multi-analyte sensing strategies towards wearable and intelligent devices.Chemical science · 2022Review
- Accurate identification of kidney injury progression via a fluorescent biosensor array.Mikrochimica acta · 2022Article
- Array-based chemical warfare agent discriminationRSC advances · 2022Article
- Polymer-based chemical-nose systems for optical-pattern recognition of gut microbiota.Chemical science · 2022Article
- An array-based nanosensor for detecting cellular responses in macrophages induced by femtomolar levels of pesticides.Chemical communications (Cambridge, England) · 2022Article
- Rapid Fluorescence Sensor Guided Detection of Urinary Tract Bacterial Infections.International journal of nanomedicine · 2022Article
- Non-invasive detection of glucose in human urine using a color-generating copper NanoZyme.Analytical and bioanalytical chemistry · 2021Article
- Article
- Pattern-recognition-based Sensor Arrays for Cell Characterization: From Materials and Data Analyses to Biomedical Applications.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2020Review
- Functionalized reduced graphene oxide with aptamer macroarray for cancer cell capture and fluorescence detection.Mikrochimica acta · 2020Article
- Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting.Nature communications · 2020Article
- SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores for In Vivo Imaging of Cell Metabolism.Angewandte Chemie (International ed. in English) · 2019Article
- Rapid Identification of Biofilms Using a Robust Multichannel Polymer Sensor Array.ACS applied materials & interfaces · 2019Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
We report a nanosensor that uses cell lysates to rapidly profile the tumorigenicity of cancer cells. This sensing platform uses host-guest interactions between cucurbit[7]uril and the cationic headgroup of a gold nanoparticle to non-covalently modify the binding of three fluorescent proteins of a multi-channel sensor in situ. This approach doubles the number of output channels to six, providing single-well identification of cell lysates with 100% accuracy. Significantly, this classification could be extended beyond the training set, determining the invasiveness of novel cell lines. The unique fingerprint of these cell lysates required minimal sample quantity (200 ng, ∼1000 cells), making the methodology compatible with microbiopsy technology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.