Evidence map›Paper›PMID 28534853›Full record

ArticleInternational journal of molecular sciences2017

The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity.

Chien-Jen Kao, Wu-Fu Chen, Bo-Lin Guo, Chien-Wei Feng, Han-Chun Hung, Wen-Ya Yang, Chun-Sung Sung, Kuan-Hao Tsui, Hsin Chu, Nan-Fu Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Chien-Jen KaoDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. kaochienjen@yahoo.com.tw.
Wu-Fu ChenDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. ma4949@cgmh.org.tw.
Bo-Lin GuoDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. askedc321@gmail.com.
Chien-Wei FengDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. qscjuejuejue@gmail.com.
Han-Chun HungDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. hanchun25@gmail.com.
Wen-Ya YangDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. s8222889@gmail.com.
Chun-Sung SungDepartment of Anesthesiology, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Road, Taipei 11217, Taiwan. sung6119@gmail.com.
Kuan-Hao TsuiDepartment of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung 804, Taiwan. khtsui60@gmail.com.
Hsin ChuNational Defense Medical Center, Department of Internal Medicine of Gangshan Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung 82049, Taiwan. hrchu@mail.ndmctsgh.edu.tw.
Nan-Fu ChenDivision of Neurosurgery, Department of Surgery, Kaohsiung Armed Forces General Hospital, Kaohsiung 804, Taiwan. chen06688@gmail.com.
Zhi-Hong WenDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan. wzh@mail.nsysu.edu.tw.
National Sun Yat-sen University · TWKaohsiung Armed Forces General Hospital · TWNational Yang Ming Chiao Tung University · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated that the marine compound austrasulfone, isolated from the soft coral

Indexed as

AnimalsAnthozoaApoptosisCaspase 3Cell LineCell SurvivalHeme Oxygenase-1HumansNeuronsNeuroprotective AgentsNeurotoxicity SyndromesOxidative StressOxidopaminep38 Mitogen-Activated Protein KinasesPentanesPentanones1-tosylpentan-3-oneCaspase 3Heme Oxygenase-1Neuroprotective AgentsOxidopaminep38 Mitogen-Activated Protein KinasesPentanesPentanonesPhosphatidylinositol 3-KinasesReactive Oxygen SpeciesTosyl Compounds1-tosylpentan-3-one6-OHDA-induced apoptosismarine compoundsneuroprotectionSH-SY5Y cellszebrafish

Identifiers

PMID28534853
PMCPMC5455005
OpenAlexW2615682514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.