Evidence map›Paper›PMID 28534852›Full record

ReviewNutrients2017

Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies.

Christophe Kosinski, François R Jornayvaz

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 6 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 6 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Pooled it
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  7. Trial
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  13. Effect of a four-week ketogenic diet on exercise metabolism in CrossFit-trained athletes.Journal of the International Society of Sports Nutrition · 2019
    Trial
  14. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Acute pancreatitis caused by severe hypertriglyceridemia in a 61-year-old man on a carnivore diet.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  19. Review
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Christophe KosinskiService of Endocrinology, Diabetes and Metabolism, Lausanne University Hospital (CHUV), Avenue de la Sallaz 8, 1011 Lausanne, Switzerland. christophe.kosinski@chuv.ch.
François R JornayvazService of Endocrinology, Diabetes, Hypertension and Nutrition, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1205 Geneva, Switzerland. ois.jornayvaz@hcuge.ch.
University Hospital of Geneva · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of obesity and cardiovascular diseases is one of the most difficult and important challenges nowadays. Weight loss is frequently offered as a therapy and is aimed at improving some of the components of the metabolic syndrome. Among various diets, ketogenic diets, which are very low in carbohydrates and usually high in fats and/or proteins, have gained in popularity. Results regarding the impact of such diets on cardiovascular risk factors are controversial, both in animals and humans, but some improvements notably in obesity and type 2 diabetes have been described. Unfortunately, these effects seem to be limited in time. Moreover, these diets are not totally safe and can be associated with some adverse events. Notably, in rodents, development of nonalcoholic fatty liver disease (NAFLD) and insulin resistance have been described. The aim of this review is to discuss the role of ketogenic diets on different cardiovascular risk factors in both animals and humans based on available evidence.

Indexed as

AnimalsCardiovascular DiseasesDiabetes Mellitus, Type 2Dietary CarbohydratesDiet, KetogenicHumansInsulin ResistanceNon-alcoholic Fatty Liver DiseaseObesityRisk FactorsDietary Carbohydratescardiovascular risk factorsfibroblast growth factor (FGF21)insulin resistanceketogenic dietsNAFLDobesitytype 2 diabetes

Identifiers

PMID28534852
PMCPMC5452247
OpenAlexW2615179214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.