ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2018
Risk factors and mechanisms of stroke in young adults: The FUTURE study.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Return to Work After Ischemic Stroke in Young Adults: A Multicenter Cohort Study, Systematic Review, and Meta-Analysis.Journal of the American Heart Association · 2025Pooled it
- Health Consequences of Intensive E-Gaming: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Pooled it
- Opium abuse and stroke in Iran: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Demographics, risk factor profiles and etiologies in young ischemic and hemorrhagic stroke - the United Kingdom Young Stroke Study (UKYSS).Journal of neurology · 2026Observational
- Exploring key stakeholder perceptions on the impact of younger stroke: a multinational, qualitative interview study.BMJ open · 2026Article
- Atherosclerotic plaque distribution and characteristics in young patients with stroke/transient ischemic attack: insights from MR vessel wall imaging and comparison with older counterparts.Quantitative imaging in medicine and surgery · 2026Article
- Comparing Clinical Characteristics and Outcomes of Tenecteplase Versus Alteplase in Young Adult Patients With Stroke: A Secondary Analysis of the AcT Trial.Stroke (Hoboken, N.J.) · 2026Article
- Ischaemic stroke in young adults: an overview of the classification, risk factors, aetiologies and outcomes.Singapore medical journal · 2026Review
- Hypertension as the Leading Cause of Stroke in Young Adults in a Northern Nigerian Hospital: A Retrospective Study.Cureus · 2026Article
- Family history of stroke and cardiovascular diseases in early-onset cryptogenic ischaemic stroke.European stroke journal · 2026Observational
- Arterial ischaemic stroke in adolescents and very young adults-results of a European cohort.European stroke journal · 2026Article
- Knowledge, Attitudes, and Practices Regarding Stroke Among Young Stroke Patients in China: A Cross-Sectional Survey.Patient preference and adherence · 2026Article
- Cognitive training improves executive function and self-efficacy in young women with chronic stroke: a pilot study.Frontiers in human neuroscience · 2025Article
- A nomogram model incorporating blood biomarkers predicts 3-week functional outcomes in stroke patients.Frontiers in neuroscience · 2025Article
- Age-dependent seasonality in the incidence of stroke: A 21-year population-based study.European stroke journal · 2024Article
- Ischemic Stroke in Young Tunisian Adults.La Tunisie medicale · 2024Article
- Association of Traditional and Nontraditional Risk Factors in the Development of Strokes Among Young Adults by Sex and Age Group: A Retrospective Case-Control Study.Circulation. Cardiovascular quality and outcomes · 2024Article
- Nomogram to predict 3 month prognosis of acute ischemic stroke among young adults.Frontiers in neurology · 2024Article
- The Role of the Low-Density Lipoprotein/High-Density Lipoprotein Cholesterol Ratio as an Atherogenic Risk Factor in Young Adults with Ischemic Stroke: A Case-Control Study.Brain sciences · 2023Article
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10 authors.
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Abstract
Incidence of ischemic stroke and transient ischemic attack in young adults is rising. However, etiology remains unknown in 30-40% of these patients when current classification systems designed for the elderly are used. Our aim was to identify risk factors according to a pediatric approach, which might lead to both better identification of risk factors and provide a stepping stone for the understanding of disease mechanism, particularly in patients currently classified as "unknown etiology". Risk factors of 656 young stroke patients (aged 18-50) of the FUTURE study were categorized according to the "International Pediatric Stroke Study" (IPSS), with stratification on gender, age and stroke of "unknown etiology". Categorization of risk factors into ≥1 IPSS category was possible in 94% of young stroke patients. Chronic systemic conditions were more present in patients aged <35 compared to patients ≥35 (32.6% vs. 15.6%, p < 0.05). Among 226 patients classified as "stroke of unknown etiology" using TOAST, we found risk factors in 199 patients (88%) with the IPSS approach. We identified multiple risk factors linked to other mechanisms of stroke in the young than in the elderly . This can be a valuable starting point to develop an etiologic classification system specifically designed for young stroke patients.
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