ReviewNeurodegenerative disease management2017
Light, sleep and circadian rhythms in older adults with Alzheimer's disease and related dementias.
Review in Neurodegenerative disease management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05535790 (PAX), which is not on this map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PAX: A Randomized Single-blind Controlled Trial of the Effect of Circadian Light on Hospitalized Persons With Dementia and Older Adults With Cognitive Impairments
Who cites it
33 citing papers in PubMed, 61 citations in OpenAlex.
- Biodynamic lighting versus bright light effects on rest-activity rhythm and night-time sleep in nursing homes residents with dementia.BMC geriatrics · 2026Trial
- Supplemental ambient lighting intervention to improve sleep in Parkinson's disease: A pilot trial.Parkinsonism & related disorders · 2024Trial
- Sexual dimorphism and photoperiodism in cognitive and neuronal ionic changes in scopolamine-induced cognitive impairment.Metabolic brain disease · 2026Article
- Sleep disturbances and Alzheimer's disease: a multiscale approach from exposome to neurobiology and precision medicine.GeroScience · 2026Review
- Using Wearable Sensors to Measure and Predict Personal Circadian Lighting Exposure in Nursing Home Residents: Model Development and Validation.JMIR aging · 2025Article
- Pilot study of dynamic lighting and sleep consolidation among older adults in a Jordanian senior care facility.Scientific reports · 2025Article
- Association of environmental exposome and cognitive function among older adults with and without preclinical Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Postoperative cognitive dysfunction: spotlight on light, circadian rhythms, and sleep.Frontiers in neuroscience · 2024Review
- Circadian Rhythm Changes in Healthy Aging and Mild Cognitive Impairment.Advanced biology · 2023Review
- Effect of Personalized Blue-Enriched White Light Intervention on Rest-Activity and Light Exposure Rhythms in Mild and Moderate Alzheimer's Disease.Psychiatry investigation · 2023Article
- Sleep Disorders Associated with Neurodegenerative Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Tunable White Light for Elders (TWLITE): A Protocol Demonstrating Feasibility and Acceptability for Deployment, Remote Data Collection, and Analysis of a Home-Based Lighting Intervention in Older Adults.Sensors (Basel, Switzerland) · 2022Article
- The Relationship Between Light Exposure before Bedtime and Daytime Sleepiness Among People Living With Cognitive Impairment.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022Article
- Light, sleep-wake rhythm, and behavioural and psychological symptoms of dementia in care home patients: Revisiting the sundowning syndrome.International journal of geriatric psychiatry · 2022Review
- Time-restricted Eating for the Prevention and Management of Metabolic Diseases.Endocrine reviews · 2022Article
- Views and experiences on the use of voice assistants by family and professionals supporting people with cognitive impairments.Frontiers in dementia · 2022Article
- Effect of Ambient Bright Light on Behavioral and Psychological Symptoms in People With Dementia: A Systematic Review.Innovation in aging · 2022Review
- Toward Quantification of Agitation in People With Dementia Using Multimodal Sensing.Innovation in aging · 2022Article
- Bright Light Therapy for Parkinson Disease: A Literature Review and Meta-Analysis of Randomized Controlled Trials.Biology · 2021Article
- Sunlight Exposure and Phototherapy: Perspectives for Healthy Aging in an Era of COVID-19.International journal of environmental research and public health · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Alzheimer's disease and related dementias (ADRD) can cause sleep and behavioral problems that are problematic for ADRD patients and their family caregivers. Light therapy has shown promise as a nonpharmacological treatment, and preliminary studies demonstrate that timed light exposure can consolidate and improve nighttime sleep efficiency, increase daytime wakefulness and reduce evening agitation without the adverse effects of pharmacological solutions. Compliance with light treatment and the accurate measurement of light exposures during treatment, however, have presented barriers for the adoption of light therapy for ADRD. Recent research showing that the circadian system is maximally sensitive to short-wavelength light opens the way for the potential application of lower, more-targeted light intensities to maximize compliance and individualize light dose/timing in therapeutic settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.