Evidence map›Paper›PMID 28534656›Full record

ArticleDevelopmental neurorehabilitation2018

Early development in Rett syndrome - the benefits and difficulties of a birth cohort approach.

Peter B Marschik, Sanne Lemcke, Christa Einspieler, Dajie Zhang, Sven Bölte, Gillian S Townend, Marlene B Lauritsen

Open access · hybridAbstract read
In one paragraph

Article in Developmental neurorehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Rett syndrome in Ireland: a demographic study.Orphanet journal of rare diseases · 2024
    Article
  7. Article
  8. Identifying Atypical Development: A Role of Day-Care Workers?Journal of autism and developmental disorders · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Peter B Marschika Institute of Physiology, Research Unit iDN - Interdisciplinary Developmental Neuroscience , Medical University of Graz , Graz , Austria.
Sanne Lemcked Centre for Child and Adolescent Psychiatry , Aarhus University Hospital , Aarhus , Denmark.
Christa Einspielera Institute of Physiology, Research Unit iDN - Interdisciplinary Developmental Neuroscience , Medical University of Graz , Graz , Austria.
Dajie Zhanga Institute of Physiology, Research Unit iDN - Interdisciplinary Developmental Neuroscience , Medical University of Graz , Graz , Austria.
Sven Bölteb Center of Neurodevelopmental Disorders (KIND), Department of Women's and Children's Health , Karolinska Institutet , Stockholm , Sweden.
Gillian S Townende Rett Expertise Centre Netherlands - GKC , Maastricht University Medical Centre , Maastricht , The Netherlands.
Marlene B Lauritsenf Research Unit for Child and Adolescent Psychiatry , Aalborg University Hospital , Aalborg , Denmark.
Medical University of Graz · ATAalborg University Hospital · DKAarhus University Hospital · DKMaastricht University Medical Centre · NLStockholm County Council · SE

Funding

Austrian Science Fund FWF P 25241
6 · The paper itself

Abstract

purposesTypically, early (pre-diagnostic) development in individuals later diagnosed with Rett syndrome (RTT) has been investigated retrospectively using parent reports, medical records and analysis of home videos. In recent years, prospective research designs have been increasingly applied to the investigation of early development in individuals with late phenotypical onset disorders, for example, autism spectrum disorder.

methodsIn this study, data collected by the Danish National Birth Cohort lent itself to prospective exploration of the early development of RTT, in particular early motor-, speech-language, and socio-communicative behaviors, mood, and sleep. RESULTS AND

conclusionsDespite limitations, this quasi prospective methodology proved promising. In order to add substantially to the body of knowledge, however, specific questions relating to peculiarites in early development could usefully be added to future cohort studies. As this involves considerable work, it may be more realistic to consider a set of indicators which point to a number of developmental disorders rather than to one.

Indexed as

Child DevelopmentAdolescentAffectChildCohort StudiesCommunicationDenmarkEarly DiagnosisFemaleHumansPhenotypeRett SyndromeSleepBirth cohortearly developmentlongitudinal studyparent interviewsprodromeRett syndrome

Identifiers

PMID28534656
PMCPMC5796587
OpenAlexW2618604574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.