Evidence map›Paper›PMID 28534319›Full record

ArticleInfection2017

Case report: human papilloma virus type 120-related papillomatosis mimicking laryngeal carcinoma.

Valeria Belvisi, Salvatore Martellucci, Anna Rosa Garbuglia, Cosmo Del Borgo, Stanislao Martellucci, Andrea Baiocchini, Anna Maria Manicone, Oreste Bagni, Claudio Maria Mastroianni, Andrea Gallo

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Valeria BelvisiDepartment of Public Health and Infectious Diseases, "Sapienza" University of Rome, Via Giulio Cesare 41\B, 04100, Latina, Italy. valeria.belvisi@gmail.com.
Salvatore MartellucciDepartment of Surgical Biotechnologies and Sciences, ENT Section, "Sapienza" University of Rome, Latina, Italy.
Anna Rosa GarbugliaLaboratory of Virology, I.N.M.I. "L. Spallanzani", IRCCS, Rome, Italy.
Cosmo Del BorgoDepartment of Public Health and Infectious Diseases, "Sapienza" University of Rome, Via Giulio Cesare 41\B, 04100, Latina, Italy.
Stanislao MartellucciDepartment of Surgical Biotechnologies and Sciences, ENT Section, "Sapienza" University of Rome, Latina, Italy.
Andrea BaiocchiniPathology Service, I.N.M.I. "L. Spallanzani", IRCCS, Rome, Italy.
Anna Maria ManiconePathology Service, "S.M. Goretti" Hospital, Latina, Italy.
Oreste BagniDepartment of Nuclear Medicine, "S.M. Goretti" Hospital, Latina, Italy.
Claudio Maria MastroianniDepartment of Public Health and Infectious Diseases, "Sapienza" University of Rome, Via Giulio Cesare 41\B, 04100, Latina, Italy.
Andrea GalloDepartment of Surgical Biotechnologies and Sciences, ENT Section, "Sapienza" University of Rome, Latina, Italy.
Sapienza University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITOspedale Santa Maria Goretti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe relationship between human papilloma virus (HPV) and upper respiratory tract pathology was better understood in recent years and represents now an issue of particular interest in carcinogenesis and in immunocompromised host. We describe a case in which a rare genotype HPV-related papillomatosis mimics laryngeal carcinoma in an immunocompromised host.

methodsA 54-year-old woman with a history of HIV-HCV coinfection and anal and laryngeal cancer successfully treated some years before was hospitalized for severe dyspnea, cough and dysphagia. Fiberoptic endoscopic evaluation raised the suspicion of tumor relapse showing the presence of a large glottic-supraglottic ulcerated mass. Several laryngeal biopsies demonstrated koilocytosis and p16 expression, according to a possible HPV infection, and focal figures of mild dysplasia of epithelium. 18 F-FDG PET/CT did not show high glycolytic activity at laryngeal level. An invasive upper respiratory tract papillomatosis in an immunocompromised host was suspected because of the patient's clinical improvement after antiretroviral therapy.

conclusionPharyngeal swab and oral rinse harboured the same HPV120 genotype sequence, a betapapillomavirus of recent description and not yet related to any similar clinical presentations.

Indexed as

BetapapillomavirusCarcinomaDiagnosis, DifferentialFemaleHumansLaryngeal NeoplasmsMiddle AgedPapillomavirus InfectionsHPV 120 genotypeHuman immunodeficiency virus (HIV)Human papilloma virus (HPV)Laryngeal papillomatosis

Identifiers

PMID28534319
OpenAlexW2618714134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.