Evidence map›Paper›PMID 28534231›Full record

ArticleInternational ophthalmology2018

Comparison of outcomes and complications of deep anterior lamellar keratoplasty and penetrating keratoplasty performed in a large group of patients with keratoconus.

Ashbala Khattak, Fouad R Nakhli, Khaled M Al-Arfaj, Abdullah A Cheema

Abstract readClinical Study
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In one paragraph

Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  11. Outcomes of deep anterior lamellar keratoplasty and penetrating keratoplasty in keratoconic eyes with and without previous hydrops.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashbala KhattakDhahran Eye Specialist Hospital, Dhahran, 31942-39455, Kingdom of Saudi Arabia. ashbalakhattak@gmail.com.
Fouad R NakhliDhahran Eye Specialist Hospital, Dhahran, 31942-39455, Kingdom of Saudi Arabia.
Khaled M Al-ArfajDammam University, Dammam, Kingdom of Saudi Arabia.
Abdullah A CheemaImperial College School of Medicine, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare visual acuity, refraction, topography, and complications of deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PKP) performed in patients with keratoconus (KCN).

methodsIn this retrospective interventional non-randomized clinical study, patients with moderate to severe KCN that underwent either PKP or DALK for optical corrections were enrolled. The final outcome analysis was performed after complete suture removal for both groups of patients. Best corrected visual acuity, spherical equivalent, refractive cylinder, average keratometry, corneal astigmatism, and endothelial cell density as well as early and late complications such as cataract, glaucoma, corneal edema, elevated intraocular pressure without visual field defect or optic disk changes, rejection, loose suture, and re-suturing were compared.

resultsTwo hundred and seven eyes were enrolled: 108 eyes underwent DALK, and 99 eyes underwent PKP for keratoconus. The mean follow-up time was 28.06 ± 12.62 months for DALK group and 29.29 ± 12.71 months for PKP. The study groups demonstrated comparable final outcome in terms of best corrected visual acuity: 0.25 ± 0.22 LogMAR and 0.28 ± 0.24 LogMAR (p = 0.415), spherical equivalent: -4.80 ± 4.55D and -3.58 ± 3.58D (p = 0.067), refractive cylinder: -3.37 ± 2.00D and -4.00 ± 2.15D (p = 0.061), average keratometry: 45.51 ± 2.30D and 44.85 ± 2.36D (p = 0.077), corneal astigmatism: 4.89 ± 3.07D and 4.63 ± 2.61D (p = 0.569) in DALK (n = 85) and PKP (n = 72), respectively. However, the postoperative endothelial cell density in DALK (n = 61) 2250 ± 450 cell/mm

conclusionThe vision, refractive error, and corneal astigmatism following DALK and PKP were comparable; however, DALK had lower incidence of long-term complications.

Indexed as

Refraction, OcularAdultCorneaCorneal TopographyFemaleFollow-Up StudiesHumansIncidenceKeratoconusKeratoplasty, PenetratingMalePostoperative ComplicationsRetrospective StudiesSaudi ArabiaTime FactorsTreatment OutcomeAnwar’s big bubbleDeep anterior lamellar keratoplastyKeratoconusPenetrating keratoplasty

Identifiers

PMID28534231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.