Evidence map›Paper›PMID 28534163›Full record

ArticleEuropean radiology2017

Differentiating metastatic from nonmetastatic lymph nodes in cervical cancer patients using monoexponential, biexponential, and stretched exponential diffusion-weighted MR imaging.

Qingxia Wu, Dandan Zheng, Ligang Shi, Mingbo Liu, Meiyun Wang, Dapeng Shi

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Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
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16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  13. Diffusion-weighted magnetic resonance imaging of primary cervical cancer in the detection of sub-centimetre metastatic lymph nodes.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qingxia WuRadiological Department of Henan Provincial People's Hospital, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Dandan ZhengGE Healthcare, MR Research China, Beijing, China.
Ligang ShiPathological Department of Henan Provincial People's Hospital, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Mingbo LiuRadiotherapeutical Department of Henan Provincial People's Hospital, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Meiyun WangRadiological Department of Henan Provincial People's Hospital, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Dapeng ShiRadiological Department of Henan Provincial People's Hospital, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China. cjr.shidapeng@vip.163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the diagnostic value of monoexponential, biexponential and stretched exponential models for identifying lymph nodes (LNs) in patients with cervical cancer. MATERIALS AND

methodsFifty female patients with cervical cancer underwent preoperative magnetic resonance imaging. The diffusion parameters of the LNs were calculated by fitting the values to monoexponential, biexponential and stretched exponential models and were compared between the metastatic and non-metastatic LN groups.

resultsA total of 157 LNs with high signal intensity on multi-b-value DWI were detected, 41 of which were pathologically shown to be metastatic. Metastatic LNs presented with higher pure water diffusion (D) values, lower perfusion fraction (f) values, higher diffusion heterogeneity (α) values, higher short diameter (Size-S), long diameter (Size-L) and short long diameter ratio (S/L Ratio) than non-metastatic LNs (P<0.05). The Size-S of LNs exhibited the highest diagnostic value, with an area under the curve of 0.844.

conclusionsCompared with the size parameters, the diffusion parameters derived from multi-b-value diffusion-weighted imaging cannot reliably discriminate metastatic from non-metastatic LNs in daily clinical routine due to limited sensitivity and specificity. KEY POINTS: • Biexponential and stretched exponential diffusion models can help to characterise LN status. • Metastatic LNs present with higher D and α values, lower f values. • Diffusion parameters were less reliable in discriminating LNs than size parameters.

Indexed as

AdenocarcinomaAdultAgedDiffusion Magnetic Resonance ImagingFemaleHumansHysterectomyLymphatic MetastasisLymph Node ExcisionLymph NodesMiddle AgedNeoplasm StagingPreoperative PeriodProspective StudiesUterine Cervical NeoplasmsCervical cancerDiffusion-weighted imagingIntravoxel incoherent motionLymph nodeMagnetic resonance imaging

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.