Evidence map›Paper›PMID 28534120›Full record

Trial reportMolecular and cellular biochemistry2017

Serum concentrations of MCP-1 and IL-6 in combination predict the presence of coronary artery disease and mortality in subjects undergoing coronary angiography.

Mohammad Tajfard, Latiffah A Latiff, Hamid Reza Rahimi, Mohsen Moohebati, Mehdi Hasanzadeh, Ahmad Sarreshtehdar Emrani, Habibollah Esmaeily, Ali Taghipour, Sayed Reza Mirhafez, Gordon A Ferns and 5 more

Open access · greenAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Molecular and cellular biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Mohammad TajfardDepartment of Health Education and Health Promotion, School of Health, Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Latiffah A LatiffDepartment of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia, Seri Kembangan, Malaysia. latiffah.latiff@gmail.com.
Hamid Reza RahimiDepartment of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohsen MoohebatiCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehdi HasanzadehCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ahmad Sarreshtehdar EmraniCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Habibollah EsmaeilyDepartment of Biostatistics & Epidemiology, School of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali TaghipourDepartment of Biostatistics & Epidemiology, School of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Sayed Reza MirhafezDepartment of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Gordon A FernsDivision of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex, BN1 9PH, UK.
Maryam Mardan-NikDepartment of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Elham MohammadzadehMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir AvanMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Parichehr HanachiDepartment of Biology, Biochemistry Unit, Alzahra University, Tehran, IR, Iran.
Majid Ghayour-MobarhanMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. ghayourm@mums.ac.ir.
Mashhad University of Medical Sciences · IRAlzahra University · IRBrighton and Sussex Medical School · GBUniversiti Putra Malaysia · MYUniversity of Neyshabur · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytokines play a key role in the pathogenesis of coronary artery disease (CAD). The aim of current study was to investigate the relationship between the serum concentrations of 12 cytokines with mortality and extent of CAD in individuals undergoing angiography and healthy controls. 342 CAD patients were recruited and divided into 2 groups: those with ≥50% occlusion in at least one coronary artery [Angiography (+)] or <50% obstruction in coronary arteries [Angiography (-)]. Also 120 healthy subjects were enrolled as control group. Lipid profile, fasting blood glucose, body mass index, and blood pressure were evaluated in all the subjects. An Evidence Investigator

Indexed as

Coronary AngiographyCoronary Artery DiseaseAdultAgedChemokine CCL2FemaleHumansInterleukin-6MaleMiddle AgedPredictive Value of TestsCCL2 protein, humanChemokine CCL2IL6 protein, humanInterleukin-6Coronary artery diseaseCytokinesLipid profileMCP-1/IL-6

Identifiers

PMID28534120
OpenAlexW2617321287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.