ArticleObstetrics & gynecology science2017
Association of isolated single umbilical artery with perinatal outcomes: Systemic review and meta-analysis.
Article in Obstetrics & gynecology science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk factors for preterm birth: an umbrella review of meta-analyses of observational studies.BMC medicine · 2023Pooled it
- Risk of developing metabolic syndrome after gestational diabetes mellitus - a systematic review and meta-analysis.Journal of endocrinological investigation · 2021Pooled it
- MR Imaging of Umbilical Cord Variations, Abnormalities, and Associated Placental Findings.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Review
- Fetal Isolated Single Umbilical Artery (ISUA) and Its Role as a Marker of Adverse Perinatal Outcomes.Journal of clinical medicine · 2024Article
- Risks of Renal Anomalies and Urinary Tract Infections in Neonates With Single Umbilical Artery.Cureus · 2024Article
- Intrauterine Growth Restriction and Placenta Previa: A Clinical Case Report of an Advanced-Age Pregnancy.Cureus · 2024Article
- Analysis of single umbilical artery with concurrent congenital anomaly: Is it a risk factor for poor prognosis? A cross-sectional study.International journal of reproductive biomedicine · 2024Article
- Perinatal Prognosis of Pregnancies with Single Umbilical Artery in a Romanian Third-Level Unit.Clinical medicine & research · 2023Article
- Prenatal Diagnosis of Isolated Single Umbilical Artery: Incidence, Risk Factors and Impact on Pregnancy Outcomes.Medicina (Kaunas, Lithuania) · 2023Article
- Prenatal diagnosis of ultrasound soft markers in a single medical center of mainland China.Molecular cytogenetics · 2023Article
- Changes in Artery Diameters and Fetal Growth in Cases of Isolated Single Umbilical Artery.Diagnostics (Basel, Switzerland) · 2023Article
- Prevalence of single umbilical artery, clinical outcomes and its risk factors: A cross-sectional study.International journal of reproductive biomedicine · 2021Article
- An epigenetic association of malformations, adverse reproductive outcomes, and fetal origins hypothesis related effects.Journal of assisted reproduction and genetics · 2018Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to evaluate the association between prenatally diagnosed isolated single umbilical artery (iSUA) and perinatal outcomes.
methodsWe searched Medline, Embase, the Cochrane Library, and KoreaMed from inception to January 2016, with no language or regional restrictions, for cohort and case-control studies reporting on the relationship of iSUA and perinatal outcomes. We assessed the odds ratios (ORs) and 95% confidence intervals (CIs) for the occurrence of small for gestational age, preterm birth, pregnancy-induced hypertension, neonatal intensive care unit admission, and perinatal mortality in fetuses with iSUA compared with those in fetuses with three vessel cord.
resultsEleven articles totaling 1,731 pregnancies with iSUA met the selection criteria. Studies varied in design, quality, outcome definition, and results. Meta-analysis carried out within predefined groups showed that the presence of an iSUA was associated with small for gestational age (OR, 2.75; 95% CI, 1.97 to 3.83;
conclusionPregnancies complicated by iSUA are at increased risk for small for gestational age, preterm birth, pregnancy-induced hypertension, neonatal intensive care unit admission and perinatal mortality. Further, large prospective cohort studies are required to improve the quality of prenatal counseling and the neonatal care for pregnancies with iSUA.
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