Evidence map›Paper›PMID 28534009›Full record

ArticleFrontiers in cellular and infection microbiology2017

Genomic Insight into Mechanisms of Reversion of Antibiotic Resistance in Multidrug Resistant

Aleksandr I Ilin, Murat E Kulmanov, Ilya S Korotetskiy, Rinat A Islamov, Gulshara K Akhmetova, Marina V Lankina, Oleg N Reva

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Whole-Genome Sequence-Based Characterization of Pre-XDRDiagnostics (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Genome analyses of 174 strains ofMicrobial genomics · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Aleksandr I IlinScientific Center for Anti-Infectious DrugsAlmaty, Kazakhstan.
Murat E KulmanovScientific Center for Anti-Infectious DrugsAlmaty, Kazakhstan.
Ilya S KorotetskiyScientific Center for Anti-Infectious DrugsAlmaty, Kazakhstan.
Rinat A IslamovScientific Center for Anti-Infectious DrugsAlmaty, Kazakhstan.
Gulshara K AkhmetovaScientific Center for Anti-Infectious DrugsAlmaty, Kazakhstan.
Marina V LankinaScientific Center for Anti-Infectious DrugsAlmaty, Kazakhstan.
Oleg N RevaDepartment of Biochemistry, Centre for Bioinformatics and Computational Biology, University of PretoriaPretoria, South Africa.
University of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug induced reversion of antibiotic resistance is a promising way to combat multidrug resistant infections. However, lacking knowledge of mechanisms of drug resistance reversion impedes employing this approach in medicinal therapies. Induction of antibiotic resistance reversion by a new anti-tuberculosis drug FS-1 has been reported. FS-1 was used in this work in combination with standard anti-tuberculosis antibiotics in an experiment on laboratory guinea pigs infected with an extensively drug resistant (XDR) strain

Indexed as

AnimalsAntibiotics, AntitubercularBase SequenceColony Count, MicrobialDisease Models, AnimalDNA, BacterialDrug CombinationsDrug Resistance, Multiple, BacterialDrug SynergismFemaleGenome, BacterialGenotypeGuinea PigsHumansIodineIodophorsAntibiotics, AntitubercularDNA, BacterialDrug CombinationsIodineIodophorspharmaceutical FS-1Polysaccharidesdrug resistance reversiongenome polymorphismMycobacterium tuberculosisnew drugnext generation sequencing

Identifiers

PMID28534009
PMCPMC5420568
OpenAlexW2614070557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.