ArticleCureus2017
Bilateral External Ventricular Drain Placement and Intraventricular Irrigation Combined with Concomitant Serial Prone Patient Positioning: A Novel Treatment for Gravity-Dependent Layering in Bacterial Ventriculitis.
Article in Cureus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06358209 (Safety and Efficacy of Ventricular Irrigation for Ventriculitis), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Ventricular Irrigation for Ventriculitis: a Randomized Controlled Trial
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Clinical effect of radical debris evacuation with a flexible neuroendoscope on patients with ventriculitis: a case series.Journal of medical case reports · 2025Article
- Neuroendoscopic lavage for the treatment of pyogenic ventriculitis in children: personal series and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Review
- Unusual case of spinal subdural empyema with ventriculitis managed conservatively with lumbar drain.BMJ case reports · 2022Article
- Successful treatment of pyogenic ventriculitis caused by extensively drug-resistantWorld journal of clinical cases · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A feared complication of ventricular access for drainage or shunting is ventriculitis. Early diagnosis and treatment is vital to prevent morbidity and mortality. Efficacy of directed antibiotic therapy in ventriculitis is limited by increasing multidrug resistant microorganisms and insufficient systemic antibiotic absorption into the cerebrospinal fluid. Treatment may involve intravenous and/or intrathecal antibiotics as well as external ventricular drainage. We present the first case report suggesting a potential role of a novel technique - direct ventricular catheter-mediated continuous saline irrigation and serial prone patient positioning - to treat a fulminant bacterial ventriculitis. This novel technique promotes egress of purulence from the ventricles and may result in more rapid control of intraventricular infectious burden.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.