Evidence map›Paper›PMID 28533893›Full record

ArticleInternational journal of molecular epidemiology and genetics2017

Expression of pattern recognition receptor genes and mortality in patients with colorectal adenocarcinoma.

Kathryn E Royse, Liang Chen, David H Berger, Michael M Ittmann, Hashem B El-Serag, Courtney J Balentine, David Y Graham, Peter A Richardson, Rolando E Rumbaut, Xiaoyun Shen and 2 more

Open access · greenAbstract read
In one paragraph

Article in International journal of molecular epidemiology and genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Significance and Role of Pattern Recognition Receptors in Malignancy.Archivum immunologiae et therapiae experimentalis · 2019
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Kathryn E RoyseDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
Liang ChenDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
David H BergerDepartment of Surgery, Baylor College of MedicineHouston 77030, TX, USA.
Michael M IttmannMichael E DeBakey Veterans Affairs Medical CenterHouston 77030, TX, USA.
Hashem B El-SeragDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
Courtney J BalentineDepartment of Surgery, Baylor College of MedicineHouston 77030, TX, USA.
David Y GrahamDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
Peter A RichardsonDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
Rolando E RumbautDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
Xiaoyun ShenPrism Genomic Medicine, Houston Medical PlazaHouston 77030, TX, USA.
Donna L WhiteDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
Li JiaoDepartment of Medicine, Baylor College of MedicineHouston 77030, TX, USA.
Michael E. DeBakey VA Medical Center · USCenter for Genomic Science · IT

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI PAVAN REDDY · 2007 to 2026
$73.9M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI FASIHA KANWAL · 2001 to 2026
$28.3M
Androgen Receptor Pathway and Risk of Hepatic Fibrosis in Hepatitis CR03DK095082 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI WHITE, DONNA LORRAINE · 2013 to 2014
$153k
NCI NIH HHS P30 CA125123NIDDK NIH HHS P30 DK056338NIDDK NIH HHS R03 DK095082
6 · The paper itself

Abstract

Toll-like receptors (TLRs) and the receptor for advanced glycation end products (AGER) are pattern recognition receptors that regulate intestinal inflammatory homeostasis. However, their relevance in colorectal cancer (CRC) prognosis is unclear. We investigated expression of

Indexed as

colorectal neoplasmsgene expressionimmuneinflammationpattern recognitionreceptor for advanced glycation end-productsreceptorssurvivalToll-like receptorstumor microenvironment

Identifiers

PMID28533893
PMCPMC5435667
OpenAlexW2982053508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.