Evidence map›Paper›PMID 28533806›Full record

ArticleJournal of contemporary brachytherapy2017

Second salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer.

Metha Maenhout, Marco van Vulpen, Marinus Moerland, Max Peters, Richard Meijer, Maurice van den Bosch, Paul Nguyen, Steven Frank, Jochem van der Voort van Zyp

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of contemporary brachytherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Focal therapy for prostate cancer: the technical challenges.Journal of contemporary brachytherapy · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Metha MaenhoutDepartment of Radiotherapy, University Medical Center Utrecht, Netherlands.
Marco van VulpenDepartment of Radiotherapy, University Medical Center Utrecht, Netherlands.
Marinus MoerlandDepartment of Radiotherapy, University Medical Center Utrecht, Netherlands.
Max PetersDepartment of Radiotherapy, University Medical Center Utrecht, Netherlands.
Richard MeijerDepartment of Urology, University Medical Center Utrecht, Netherlands.
Maurice van den BoschDepartment of Radiology, University Medical Center Utrecht, Netherlands.
Paul NguyenDepartment of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
Steven FrankDepartment of Radiotherapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jochem van der Voort van ZypDepartment of Radiotherapy, University Medical Center Utrecht, Netherlands.
University Medical Center Utrecht · NLDana-Farber Brigham Cancer Center · USThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSalvage treatments for localized radiorecurrent prostate cancer can be performed safely when a focal and image guided approach is used. Due to the low toxicity, the opportunity exists to investigate a second salvage treatment when a second locally recurrent prostate cancer occurs. Here, we describe a second salvage treatment procedure of 4 patients. MATERIAL AND

methodsFour patients with a pathologically proven second local recurrence were treated in an outpatient magnetic resonance imaging (MRI)-guided setting with a single fraction of 19 Gy focal high-dose-rate brachytherapy (HDR-BT). Delineation was performed using choline-PET-CT or a

resultsWith a median follow-up of 12 months (range, 6-15), there were 2 patients with biochemical recurrence as defined by the Phoenix-definition. There were no patients with grade 3 or more toxicity. In all second salvage HDR-BT treatments, the constraints for rectum, bladder, and urethra were met. Median treatment volume (GTV) was 4.8 cc (range, 1.9-6.6 cc). A median of 8 catheters (range, 6-9) were used, and the median dose to the treatment volume (GTV) was a D

conclusionsSecond focal salvage MRI-guided HDR-BT for a select group of patients with a second locally recurrent prostate cancer is feasible. There was no grade 3 or more acute toxicity for these four patients.

Indexed as

HDR brachytherapyMRI guidedrecurrent prostate cancersecond salvage treatment

Identifiers

PMID28533806
PMCPMC5437080
OpenAlexW2604827451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.