Evidence map›Paper›PMID 28533714›Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2016

microRNAs in ischaemic cardiovascular diseases.

Simona Greco, Germana Zaccagnini, Christine Voellenkle, Fabio Martelli

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. MicroRNA-369 attenuates hypoxia-induced cardiomyocyte apoptosis and inflammation via targeting TRPV3.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
  2. Article
  3. Role of miRNAs in hypoxia-related disorders.Journal of biosciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Simona GrecoMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, via Morandi 30, 20097 San Donato Milanese, Milan, Italy.
Germana ZaccagniniMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, via Morandi 30, 20097 San Donato Milanese, Milan, Italy.
Christine VoellenkleMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, via Morandi 30, 20097 San Donato Milanese, Milan, Italy.
Fabio MartelliMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, via Morandi 30, 20097 San Donato Milanese, Milan, Italy.
IRCCS Policlinico San Donato · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

microRNAs (miRNAs) are non-coding RNA molecules that modulate the stability and/or the translational efficiency of specific messenger RNAs. They have been shown to play a regulatory role in most biological processes and their expression is disrupted in many cardiovascular diseases. This review describes studies performed at Policlinico San Donato-IRCCS in cell cultures, animal models, and patients, showing a penetrant role of miRNAs in cell response to hypoxia and in ischaemic cardiovascular diseases. These experiments indicate miRNA as an emerging class of therapeutic targets.

Indexed as

Cardiovascular diseasesHypoxiaIschaemiamicroRNA

Identifiers

PMID28533714
OpenAlexW2342889876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.