Evidence map›Paper›PMID 28533610›Full record

ArticleJournal of physical therapy science2017

Effects of transcutaneous electrical nerve stimulation on chemotherapy-induced peripheral neuropathy symptoms (CIPN): a preliminary case-control study.

Tania Tonezzer, Leonardo Affonso Massabki Caffaro, Katiuscia Rosette Scasni Menon, Fabíola Cristina Brandini da Silva, Christina May Moran de Brito, Almir José Sarri, Raquel Aparecida Casarotto

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of physical therapy science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. BeyondFrontiers in pain research (Lausanne, Switzerland) · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Review
  8. Integrated Medicine for Chemotherapy-Induced Peripheral Neuropathy.International journal of molecular sciences · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tania TonezzerDepartment of Rehabilitation Sciences in the School of Medicine, Department of Physical Therapy, Speech and Occupational Therapy, University of São Paulo, Brazil.
Leonardo Affonso Massabki CaffaroDepartment of Rehabilitation Sciences in the School of Medicine, Department of Physical Therapy, Speech and Occupational Therapy, University of São Paulo, Brazil.
Katiuscia Rosette Scasni MenonDepartment of Physiotherapy Course of University of São Francisco, Brazil.
Fabíola Cristina Brandini da SilvaBarretos Cancer Hospital, Brazil.
Christina May Moran de BritoRehabilitation Department of the Cancer Institute at the University of São Paulo School of Medicine, Brazil.
Almir José SarriDepartment of Physiotherapy, Barretos Cancer Hospital, Brazil.
Raquel Aparecida CasarottoDepartment of Physical Therapy, Speech and Occupational Therapy, School of Medicine of the University of São Paulo, Brazil.
Universidade de São Paulo · BRHospital de Câncer de Barretos · BRUniversidade São Francisco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[Purpose] The aim of this double-blind, randomized and placebo-controlled study is to investigate the effects of Transcutaneous Electrical Nerve Stimulation for reducing the side effects of Chemotherapy-induced Peripheral Neuropathy in cancer patients undergoing chemotherapy with oxaloplatin or paclitaxel. [Subjects and Methods] Twenty-four patients were randomly allocated into two groups: active or placebo stimulation. All patients were assessed for pain, numbness/tingiling, frequency of symptoms, and quality of life. The transcutaneous Electrical Nerve Stimulation device was applied daily with modulating frequencies ranging between 7 Hz and 65 Hz in distal limb regions during three cycles of chemotherapy (45 days). The other stimulation parameters were: pulse duration of 200 μsec, intensity at the highest tolerable level, and increases in intensity when it diminished. [Results] The data showed no difference between active or placebo groups in terms of pain, numbness/tingling, frequency of symptoms or impact on daily life activities. [Conclusion] These results suggest that Transcutaneous Electrical Nerve Stimulation applied in the frequency variation mode was not proven to be effective to improve the symptoms of Chemotherapy-induced Peripheral Neuropathy during chemotherapy cycles. There was no worsening of symptoms in subsequent cycles of the onset of symptoms of the disease.

Indexed as

Chemotherapy-induced peripheral neuropathyPhysical therapyTranscutaneous electric nerve stimulation

Identifiers

PMID28533610
PMCPMC5430273
OpenAlexW2606408170

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.