Evidence map›Paper›PMID 28533567›Full record

ArticleTetrahedron letters2016

Synthesis and incorporation of a caged tyrosine amino acid possessing a bioorthogonal handle.

Marshall S Padilla, Christopher A Farley, Lindsay E Chatkewitz, Douglas D Young

Open access · greenAbstract read
In one paragraph

Article in Tetrahedron letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marshall S PadillaDepartment of Chemistry, College of William & Mary, P.O. Box 8795, Williamsburg, VA 23187, USA.
Christopher A FarleyDepartment of Chemistry, College of William & Mary, P.O. Box 8795, Williamsburg, VA 23187, USA.
Lindsay E ChatkewitzDepartment of Chemistry, College of William & Mary, P.O. Box 8795, Williamsburg, VA 23187, USA.
Douglas D YoungDepartment of Chemistry, College of William & Mary, P.O. Box 8795, Williamsburg, VA 23187, USA.
William & Mary · US

Funding

Bioconjugations Employing Unnatural Amino AcidsR15GM113203 · NIGMS · COLLEGE OF WILLIAM AND MARY · PI YOUNG, DOUGLAS · 2016 to 2025
$1.0M
NIGMS NIH HHS R15 GM113203
6 · The paper itself

Abstract

Reversing a bioconjugation in a spatial and temporal fashion has widespread applications, especially toward targeted drug delivery. We report the synthesis and incorporation of an unnatural amino acid with an alkyne modified dimethoxy-

Indexed as

AlkynesBioconjugationPhotoregulationUnnatural amino acids

Identifiers

PMID28533567
PMCPMC5438197
OpenAlexW2520640141

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.