Evidence map›Paper›PMID 28533429›Full record

ArticleThe Journal of biological chemistry2017

The fibrinogen-like domain of FREP1 protein is a broad-spectrum malaria transmission-blocking vaccine antigen.

Guodong Niu, Caio Franc A, Genwei Zhang, Wanlapa Roobsoong, Wang Nguitragool, Xiaohong Wang, Jetsumon Prachumsri, Noah S Butler, Jun Li

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
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  11. Article
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  13. Article
  14. Evolution and assembly ofOpen biology · 2023
    Article
  15. Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.Frontiers in cellular and infection microbiology · 2023
    Article
  16. Review
  17. Article
  18. Frontiers in immunology · 2022
    Review
  19. Gene drives gaining speed.Nature reviews. Genetics · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guodong NiuDepartment of Biological Sciences, Florida International University, Miami, Florida 33199.
Caio Franc ADepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019.
Genwei ZhangDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019.
Wanlapa RoobsoongMahidol Vivax Research Center, Mahidol University Faculty of Tropical Medicine, Bangkok 10400, Thailand.
Wang NguitragoolMahidol Vivax Research Center, Mahidol University Faculty of Tropical Medicine, Bangkok 10400, Thailand.
Xiaohong WangDepartment of Biological Sciences, Florida International University, Miami, Florida 33199.
Jetsumon PrachumsriMahidol Vivax Research Center, Mahidol University Faculty of Tropical Medicine, Bangkok 10400, Thailand.
Noah S ButlerDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa 52242.
Jun LiDepartment of Biological Sciences, Florida International University, Miami, Florida 33199; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019. Electronic address: lij@fiu.edu.

Funding

Fungal metabolites block malaria transmissionR01AI125657 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI LI, JUN · 2017 to 2021
$2.5M
Targeting Mosquito FREP1 Protein for Malaria ControlR21AI115178 · NIAID · UNIVERSITY OF OKLAHOMA · PI LI, JUN · 2015 to 2016
$421k
NIAID NIH HHS R01 AI125657NIAID NIH HHS R21 AI115178
6 · The paper itself

Abstract

FREP1 in mosquito midguts facilitates

Indexed as

Amino Acid SequenceAnimalsAnophelesAntibodies, BlockingConserved SequenceFemaleGerm CellsHumansInsect ProteinsMalaria, FalciparumMalaria VaccinesMalaria, VivaxMaleMicePeptide FragmentsPlasmodium bergheiAntibodies, BlockingInsect ProteinsMalaria VaccinesPeptide FragmentsRecombinant ProteinsVaccines, Syntheticinfectionligand-binding proteinmalariamalaria transmission–blocking vaccineparasitevaccine

Identifiers

PMID28533429
PMCPMC5512087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.