Evidence map›Paper›PMID 28533408›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

RNA editing of

Li Fu, Yan-Ru Qin, Xiao-Yan Ming, Xian-Bo Zuo, Yu-Wen Diao, Li-Yi Zhang, Jiaoyu Ai, Bei-Lei Liu, Tu-Xiong Huang, Ting-Ting Cao and 13 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 3 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. REMR: Identification of RNA Editing-mediated MiRNA Regulation in Cancers.Computational and structural biotechnology journal · 2024
    Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 10 institutions in 3 countries.

Li FuDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060; gracelfu@szu.edu.cn xyguan@hku.hk.
Yan-Ru QinDepartment of Clinical Oncology, the First Affiliated Hospital, Zhengzhou University, Zhengzhou, China 450000.
Xiao-Yan MingDepartment of Clinical Oncology, University of Hong Kong, Hong Kong, China.
Xian-Bo ZuoDepartment of Dermatology, the First Affiliated Hospital of Anhui Medical University, Hefei, China 230000.
Yu-Wen DiaoDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060.
Li-Yi ZhangDepartment of Clinical Oncology, University of Hong Kong, Hong Kong, China.
Jiaoyu AiDepartment of Clinical Oncology, the First Affiliated Hospital, Zhengzhou University, Zhengzhou, China 450000.
Bei-Lei LiuDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060.
Tu-Xiong HuangDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060.
Ting-Ting CaoDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060.
Bin-Bin TanDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060.
Di XiangDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060.
Chui-Mian ZengDepartment of Pharmacology, Shenzhen University School of Medicine, Shenzhen, China 518060.
Jing GongMOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing 100084, China.
Qiangfeng ZhangMOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing 100084, China.
Sui-Sui DongDepartment of Clinical Oncology, University of Hong Kong, Hong Kong, China.
Juan ChenDepartment of Clinical Oncology, University of Hong Kong, Hong Kong, China.
Haibo LiuKey Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China 510150.
Jian-Lin WuState Key Laboratory for Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.
Robert Z QiDepartment of Biochemistry, Hong Kong University of Sciences and Technology, Hong Kong, China.
Dan XieState Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China 510275.
Li-Dong WangHenan Key Laboratory for Esophageal Cancer Research of the First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, China 450000.
Xin-Yuan GuanDepartment of Clinical Oncology, University of Hong Kong, Hong Kong, China; gracelfu@szu.edu.cn xyguan@hku.hk.ORCID 0000-0002-4485-6017
Shenzhen University · CNUniversity of Hong Kong · HKCenter for Life Sciences · CNFirst Affiliated Hospital of Zhengzhou University · CNSun Yat-sen University · CNHong Kong University of Science and Technology · HKMacau University of Science and Technology · MOMinistry of Education of the People's Republic of China · CNThird Affiliated Hospital of Guangzhou Medical University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Like many complex human diseases, esophageal squamous cell carcinoma (ESCC) is known to cluster in families. Familial ESCC cases often show early onset and worse prognosis than the sporadic cases. However, the molecular genetic basis underlying the development of familial ESCC is mostly unknown. We reported that

Indexed as

RNA EditingActininAdenosine DeaminaseAdultAgedAnimalsCarcinoma, Squamous CellCell LineCell Line, TumorCell MovementDisease ProgressionDown-RegulationEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaEsophagusGene Knockdown TechniquesActininACTN4 protein, humanADARB1 protein, humanAdenosine DeaminaseOrganic Cation Transporter 3Organic Cation Transport ProteinsRNA-Binding ProteinsADAR2familial ESCCmetastasis suppressorRNA editingSLC22A3

Identifiers

PMID28533408
PMCPMC5468658
OpenAlexW2617975362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.