Evidence map›Paper›PMID 28533330›Full record

ArticleHypertension (Dallas, Tex. : 1979)2017

Race and Sex Differences of Long-Term Blood Pressure Profiles From Childhood and Adult Hypertension: The Bogalusa Heart Study.

Wei Shen, Tao Zhang, Shengxu Li, Huijie Zhang, Bo Xi, Hongbing Shen, Camilo Fernandez, Lydia Bazzano, Jiang He, Wei Chen

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005129 (The Bogalusa Heart Study), which is not on this map. Cited by 72 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 4 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005129 active not recruitingnot on this map

The Bogalusa Heart Study

TypeobservationalSponsorTulane UniversityRan1973 to 2029Enrolled11,737ConditionsAtherosclerosis, Cardiovascular Diseases, Heart Diseases, Coronary Disease
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 4 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Exploratory thresholds for ambient PMBMC public health · 2026
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  19. Secular trends in blood pressure among university students in Japan over the last two decades.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wei ShenFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Tao ZhangFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Shengxu LiFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Huijie ZhangFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Bo XiFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Hongbing ShenFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Camilo FernandezFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Lydia BazzanoFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Jiang HeFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.).
Wei ChenFrom the Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA (W.S., T.Z., S.L., H.Z., B.X., C.F., L.B., J.H., W.C.); Department of Epidemiology, School of Public Health, Nanjing Medical University, China (H.S.); Department of Biostatistics, School of Public Health, Shandong University, Jinan, China (T.Z., B.X.); and Department of Endocrinology and Metabolism, the First Affiliated Hospital of Xiamen University, China (H.Z.). wchen1@tulane.edu.
Nanjing Medical University · CNShandong University · CN

Funding

Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Elizabeth Engler-Chiurazzi · 2016 to 2026
$25.3M
Childhood CV Risk and Adult CVD Outcomes: an International Long-term Follow-upR01HL121230 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI BURNS, TRUDY L, CHEN, WEI · 2015 to 2019
$13.3M
EVOLUTION OF CARDIOVASCULAR RISK WITH NORMAL AGINGR01AG016592 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2000 to 2015
$11.7M
Lifespan Cardiovascular Risk Exposures and Alzheimer-related brain health: Bogalusa Heart StudyRF1AG041200 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI BAZZANO, LYDIA, CARMICHAEL, OWEN T. · 2019 to 2022
$4.2M
The Role of Vascular Aging in Cognitive and Physical Function - Diversity SupplementR01AG041200 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI BAZZANO, LYDIA · 2012 to 2017
$2.9M
Childhood Secondhand Smoke and Longitudinal Cardiovascular Risk ProfileR01ES021724 · NIEHS · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, WEI · 2012 to 2014
$1.8M
Research Training in Gene-Environment Interaction in ChinaD43TW009107 · FIC · TULANE UNIVERSITY OF LOUISIANA · PI GU, DONGFENG, HE, JIANG · 2012 to 2016
$1.1M
FIC NIH HHS D43 TW009107NHLBI NIH HHS R01 HL121230NIA NIH HHS R01 AG016592NIA NIH HHS RF1 AG041200NIEHS NIH HHS R01 ES021724NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

This study aims to characterize longitudinal blood pressure (BP) trajectories from childhood in black-white and sex groups and examine the association between childhood level-independent trajectories of BP and adult hypertension. The longitudinal cohort consisted of 2732 adults who had body mass index and BP measured 4 to 15 times from childhood (4-19 years) to adulthood (20-51 years). Model-estimated levels and linear slopes of BP and body mass index at childhood age points were calculated at 1-year intervals using the growth curve parameters and their first derivatives, respectively. Linear and nonlinear curve parameters differed significantly between race-sex groups; BP levels showed race and sex differences 15 years of age onward. Hypertensives had higher long-term BP levels than normotensives in race-sex groups. Although linear and nonlinear slope parameters of BP were race and sex specific, they differed consistently, significantly between hypertension and normotension groups. BP trajectories during young adulthood (20-35 years) were significantly greater in hypertensives than in normotensives; however, the trajectories during middle-aged adulthood (36-51 years) were significantly smaller in hypertensives than in normotensives. Level-independent linear slopes of systolic BP showed significantly negative associations (odds ratio=0.50≈0.76;

Indexed as

Blood Pressure DeterminationHypertensionAdolescentAdultAge of OnsetBlack or African AmericanBlack PeopleBlood PressureChild, PreschoolCross-Sectional StudiesHumansLife StyleLouisianaMiddle AgedRisk FactorsSex Factorsblood pressurecardiovascular diseasehypertensionlongitudinal studyprevalence

Identifiers

PMID28533330
PMCPMC5711390
OpenAlexW2754762020

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.