Evidence map›Paper›PMID 28533236›Full record

ArticleAntimicrobial agents and chemotherapy2017

Antibacterial and Antibiofilm Activities of a Novel Synthetic Cyclic Lipopeptide against Cariogenic Streptococcus mutans UA159.

Kyung R Min, Adriana Galvis, Brandon Williams, Ramanjaneyulu Rayala, Predrag Cudic, Dragana Ajdic

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Peptide Designs for Use in Caries Management: A Systematic Review.International journal of molecular sciences · 2023
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Frontiers in pharmacology · 2021
    Article
  11. Hindering of CariogenicBiomolecules · 2020
    Article
  12. Antimicrobial Peptide-Polymer Conjugates for Dentistry.ACS applied polymer materials · 2020
    Article
  13. Article
  14. Article
  15. Peptide Mediated Antimicrobial Dental Adhesive System.Applied sciences (Basel, Switzerland) · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kyung R MinDepartment of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Adriana GalvisDepartment of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Brandon WilliamsDepartment of Chemistry and Biochemistry, Center for Molecular Biology and Biotechnology, Florida Atlantic University, Jupiter, Florida, USA.
Ramanjaneyulu RayalaDepartment of Chemistry and Biochemistry, Center for Molecular Biology and Biotechnology, Florida Atlantic University, Jupiter, Florida, USA.
Predrag CudicDepartment of Chemistry and Biochemistry, Center for Molecular Biology and Biotechnology, Florida Atlantic University, Jupiter, Florida, USA.
Dragana AjdicDepartment of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA d.ajdic@med.miami.edu.
Florida Atlantic University · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite continuous efforts to control cariogenic dental biofilms, very few effective antimicrobial treatments exist. In this study, we characterized the activity of the novel synthetic cyclic lipopeptide 4 (CLP-4), derived from fusaricidin, against the cariogenic pathogen

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBiofilmsCell LineDental CariesDental PlaqueDepsipeptidesHumansLipopeptidesMicrobial Sensitivity TestsPeptides, CyclicProteolysisStreptococcus mutansAnti-Bacterial AgentsBacterial Proteinscyclic lipopeptide 4Depsipeptidesfusaricidin ALipopeptidesPeptides, Cyclicantimicrobial peptidecyclic lipopeptidedental biofilmsdental plaqueStreptococcus mutans

Identifiers

PMID28533236
PMCPMC5527655
OpenAlexW2616950485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.