ArticleVeterinary microbiology2017
A molecular survey for selected viral enteropathogens revealed a limited role of Canine circovirus in the development of canine acute gastroenteritis.
Article in Veterinary microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Molecular and serological surveys of canine distemper virus: A meta-analysis of cross-sectional studies.PloS one · 2019Pooled it
- Detection of canine circovirus (CanineCV) co-infection in canine parvovirus 2 (CPV-2) cases among domestic dogs in Vietnam, 2023-2024.Archives of virology · 2026Article
- Detection of canine circovirus (CanineCV) co-infection in canine parvovirus 2 (CPV-2) cases among domestic dogs in Vietnam, 2023-2024.Archives of virology · 2026Article
- Clinicopathological profiling of diarrheic canine parvovirus-circovirus co-infections in Hanoi, Vietnam.Open veterinary journal · 2026Article
- Molecular Epidemiology of Highly Diffusive DNA Viruses in Dogs and Cats from Romania.Animals : an open access journal from MDPI · 2025Article
- Molecular Survey for Major Canine Enteric Viral Pathogens in Wild Carnivores, Northwestern Italy.Veterinary sciences · 2025Article
- Canine circovirus: an emerging virus of dogs and wild canids.Irish veterinary journal · 2025Review
- Canine circovirus: emergence, adaptation, and challenges for animal and public health.Frontiers in veterinary science · 2025Review
- Molecular characterization of canine circovirus based on the Capsid gene in Thailand.BMC veterinary research · 2024Article
- Recombinantly expressed virus-like particles (VLPs) of canine circovirus for development of an indirect ELISA.Veterinary research communications · 2024Article
- Article
- Recombinant expression and characterization of Canine circovirus capsid protein for diagnosis.Frontiers in veterinary science · 2024Article
- Investigation of canine chaphamaparvovirus, canine bufavirus, and canine adenovirus in dogs with diarrhea: First report of novel canine bufavirus in Turkey.Virus genes · 2023Article
- Persistence of DNA from canine parvovirus modified-live virus in canine tissues.Veterinary research communications · 2023Article
- Molecular analysis of canine circovirus in dogs from animal shelters in Belém, Pará, northern Brazil: first detection at the amazon region.Brazilian journal of veterinary medicine · 2023Article
- Canine circovirus among dogs and cats in China: first identification in cats.Frontiers in microbiology · 2023Article
- Canine circovirus genomic characterization in dogs with and without diarrheal syndrome in Medellín, Colombia.Frontiers in veterinary science · 2023Article
- Canine circovirus: An emerging or an endemic undiagnosed enteritis virus?Frontiers in veterinary science · 2023Review
- Coinfection with canine distemper virus and canine circovirus in a dog in Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Study on the Canine Adenovirus Type 1 (CAdV-1) Infection in Domestic Dogs in Southern Italy.Pathogens (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Canine circovirus (CanineCV) is a canine virus, whose pathogenetic role is still uncertain. Based on recent data suggesting its role as entheropathogen, a case-control study was conducted between 2013 and 2016 to investigate the association of CanineCV with gastroenteritis in dogs, alone or in combination with other viral pathogens, including canine parvovirus (CPV), canine coronavirus (CCoV) and canine distemper virus (CDV). A total of 219 dogs suffering from acute gastroenteritis disorders and 67 controls randomly recruited among healthy dogs or patients presenting without enteric signs were screened by a panel of real-time (RT-)PCR assays for CanineCV, CPV, CCoV and CDV. A high prevalence of viral infections was detected in dogs with gastroenteritis (77.16%), with CPV representing the most frequently detected enteropathogen, followed by CanineCV and CCoV. While CPV and CCoV infections displayed a strong association with occurrence of acute gastroenteritis (p<0.00001), detection of CanineCV in control dogs (28.35%) occurred with prevalence comparable to that of clinical cases (32.42%), so that its correlation with gastrointestinal disease was not statistically supported (p=0.530988). Different from the clinical cases, where co-infections were frequently observed, all positive samples from the control group contained single infections. Noteworthy, a significant association was calculated between co-infections with CanineCV and occurrence of acute gastroenteritis (p<0.00001). This study supports the role of CanineCV as a co-pathogen in the development of gastrointestinal disease, mainly acting in synergism with other enteric viruses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.