Evidence map›Paper›PMID 28532708›Full record

ArticleKidney international2017

High hepatitis C viral load and genotype 2 are strong predictors of chronic kidney disease.

Tai-Shuan Lai, Mei-Hsuan Lee, Hwai-I Yang, San-Lin You, Sheng-Nan Lu, Li-Yu Wang, Yong Yuan, Gilbert L'Italien, Kuo-Liong Chien, Chien-Jen Chen and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Kidney international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Renal Function in Chronic Hepatitis C Patients in Mongolia.Diagnostics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. The association between hepatitis C virus infection and renal function.Journal of the Chinese Medical Association : JCMA · 2021
    Article
  12. UEG Week 2019 Poster Presentations.United European gastroenterology journal · 2019
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Hepatitis C virus infection and chronic renal disease: A review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018
    Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Tai-Shuan LaiDepartment of Internal Medicine, National Taiwan University Hospital, Bei-Hu branch, Taipei, Taiwan; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Mei-Hsuan LeeInstitute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
Hwai-I YangGenomics Research Center, Academia Sinica, Taipei, Taiwan.
San-Lin YouSchool of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan; Big Data Research Center, Fu-Jen Catholic University, New Taipei City, Taiwan.
Sheng-Nan LuDepartment of Gastroenterology, Kaohsiung Chang-Gung Memorial Hospital, Kaohsiung, Taiwan.
Li-Yu WangDepartment of Medicine, Mackay Medical College, New Taipei City, Taiwan.
Yong YuanGlobal Health Economics and Outcomes Research, Bristol-Myers Squibb, Princeton, New Jersey, USA.
Gilbert L'ItalienGlobal Health Economics and Outcomes Research, Bristol-Myers Squibb, Princeton, New Jersey, USA; Yale University School of Medicine, New Haven, Connecticut, USA.
Kuo-Liong ChienInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan. Electronic address: klchien@ntu.edu.tw.
Chien-Jen ChenInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan; Genomics Research Center, Academia Sinica, Taipei, Taiwan. Electronic address: chencj@gate.sinica.edu.tw.
REVEAL-HCV Study Group
Bristol-Myers Squibb (United States) · USGenomics Research Center, Academia Sinica · TWFu Jen Catholic University · TWKaohsiung Chang Gung Memorial Hospital · TWMackay Medical College · TWNational Taiwan University · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Associations between chronic hepatitis C virus (HCV) infection and chronic kidney disease (CKD) remain controversial. Here we aimed to clarify the association between HCV viral load, genotype, and CKD in 13,805 participants aged 30-65 years enrolled in the REVEAL-HCV Study, a community-based prospective study conducted in 1991-1992. CKD was defined by consecutive proteinuria or an estimated glomerular filtration rate (eGFR) under 60 mL/min/1.73 m

Indexed as

Viral LoadAdultFemaleGenotypeGlomerular Filtration RateHepacivirusHepatitis C, ChronicHumansLiver Function TestsLogistic ModelsMaleMiddle AgedOdds RatioPrevalenceProspective StudiesProteinuriaRNA, Viralchronic kidney diseasegenotypehepatitis Cprevalenceviral load

Identifiers

PMID28532708
OpenAlexW2616284824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.