Evidence map›Paper›PMID 28532499›Full record

Trial reportTrials2017

Laparoscopic Roux-en-Y gastric bypass versus laparoscopic mini gastric bypass in the treatment of obesity: study protocol for a randomized controlled trial.

Marko Kraljević, Tarik Delko, Thomas Köstler, Elena Osto, Thomas Lutz, Sarah Thommen, Raoul A Droeser, Lincoln Rothwell, Daniel Oertli, Urs Zingg

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02601092 (Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Mini Gastric Bypass), which is not on this map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02601092 naunknown statusnot on this map

Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Mini Gastric Bypass: A Randomized Controlled Trial

TypeinterventionalSponsorSpital Limmattal SchlierenRan2016 to 2020Enrolled80ConditionsObesity, Bypass ComplicationsArmsMini Gastric Bypass, Roux-en-Y Gastric Bypass
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Marko KraljevićDepartment of General Surgery, University Hospital Basel, 4031, Basel, Switzerland. marko.kraljevic@gmail.com.
Tarik DelkoDepartment of General Surgery, University Hospital Basel, 4031, Basel, Switzerland.
Thomas KöstlerDepartment of General Surgery, Limmattal Hospital, 8952, Zurich-Schlieren, Switzerland.
Elena OstoIFNH Laboratory of Translational Nutrition Biology, ETH Zurich, 8603, Schwerzenbach, Switzerland.
Thomas LutzInstitute of Veterinary Physiology, Vetsuisse Faculty and Centre of Integrative Human Physiology, University of Zurich, 8057, Zurich, Switzerland.
Sarah ThommenBasel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, 4031, Basel, Switzerland.
Raoul A DroeserDepartment of General Surgery, University Hospital Basel, 4031, Basel, Switzerland.
Lincoln RothwellDepartment of General Surgery, Ipswich General Hospital, Ipswich, Queensland, 4305, Australia.
Daniel OertliDepartment of General Surgery, University Hospital Basel, 4031, Basel, Switzerland.
Urs ZinggDepartment of General Surgery, Limmattal Hospital, 8952, Zurich-Schlieren, Switzerland.
University Hospital of Basel · CHSpital Limmattal · CHETH Zurich · CHIpswich Hospital · AUUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic Roux-en-Y gastric bypass (LRYGB) is considered the gold standard in bariatric surgery, achieving durable long-term weight loss with improvement of obesity-related comorbidities. Lately, the laparoscopic mini gastric bypass (LMGB) has gained worldwide popularity with similar results to LRYGB in terms of weight loss and comorbidity resolution. However, there is a lack of randomized controlled trials (RCT) comparing LMGB and LRYGB. This article describes the design and protocol of a randomized controlled trial comparing the outcomes of these two bariatric procedures. METHODS/

designThe trial is designed as a single center, randomized, patient and observer blinded trial. The relevant ethics committee has approved the trial protocol. To demonstrate that LMGB is not inferior to LRYGB in terms of excess weight loss (EWL) the study is conducted as a non-inferiority trial with the sample-size calculations performed accordingly. EWL 12 months after surgery is the primary endpoint, whereas 3-year EWL, morbidity, mortality, remission of obesity related comorbidities, quality of life (QOL) and hormonal and lipid profile changes are secondary endpoints. Eighty patients, 18 years or older and with a body mass index (BMI) between 35 and 50 kg/m DISCUSSION: With its 3-year follow up time, this RCT will provide important data on the impact of LMGB and LRYGB on EWL, remission of comorbidities, QOL and hormonal and lipid profile changes.

trial registrationClinicalTrials.gov, NCT02601092 . Registered on 28 September 2015.

Indexed as

LaparoscopyBiomarkersBody Mass IndexClinical ProtocolsComorbidityGastric BypassHormonesHumansLipidsObesity, MorbidQuality-Adjusted Life YearsSample SizeSwitzerlandTime FactorsTreatment OutcomeWeight LossBiomarkersHormonesLipidsExcess weight lossMini gastric bypassOutcomeRandomized controlled trialRoux-en-Y gastric bypass

Identifiers

PMID28532499
PMCPMC5441098
OpenAlexW2618069403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.