Evidence map›Paper›PMID 28532488›Full record

ArticleHarm reduction journal2017

Mitigating the heroin crisis in Baltimore, MD, USA: a cost-benefit analysis of a hypothetical supervised injection facility.

Amos Irwin, Ehsan Jozaghi, Brian W Weir, Sean T Allen, Andrew Lindsay, Susan G Sherman

Abstract read
In one paragraph

Article in Harm reduction journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Supervised consumption sites and population-level overdose mortality: a systematic review of recent evidence, 2016-2024.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Pooled it
  2. Economic Evaluations of Establishing Opioid Overdose Prevention Centers in 12 North American Cities: A Systematic Review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2024
    Pooled it
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  8. Methicillin-resistantJournal of the American College of Emergency Physicians open · 2025
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  16. Acceptability of Overdose Prevention Sites in the Business Community in Baltimore, Maryland.Journal of urban health : bulletin of the New York Academy of Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amos IrwinLaw Enforcement Action Partnership, Silver Spring, MD, USA. Amos@LawEnforcementAction.org.
Ehsan JozaghiBritish Columbia Centre for Disease Control, University of British Columbia, Vancouver, Canada.
Brian W WeirDepartment of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Sean T AllenDepartment of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Andrew LindsayDepartment of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Susan G ShermanCriminal Justice Policy Foundation, Amherst College, Silver Spring, MD, USA.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
NIDA Epidemiology Training Program: Johns Hopkins UniversityT32DA007292 · NIDA · JOHNS HOPKINS UNIVERSITY · PI RENEE M. JOHNSON, Brion S Maher · 1993 to 2026
$17.7M
Research Infrastructure for the Hopkins Population CenterR24HD042854 · NICHD · JOHNS HOPKINS UNIVERSITY · PI HAO, LINGXIN · 2003 to 2017
$5.1M
CIHR 201511MFE-358449-223266NIAID NIH HHS P30 AI094189NICHD NIH HHS R24 HD042854NIDA NIH HHS T32 DA007292
6 · The paper itself

Abstract

backgroundIn Baltimore, MD, as in many cities throughout the USA, overdose rates are on the rise due to both the increase of prescription opioid abuse and that of fentanyl and other synthetic opioids in the drug market. Supervised injection facilities (SIFs) are a widely implemented public health intervention throughout the world, with 97 existing in 11 countries worldwide. Research has documented the public health, social, and economic benefits of SIFs, yet none exist in the USA. The purpose of this study is to model the health and financial costs and benefits of a hypothetical SIF in Baltimore.

methodsWe estimate the benefits by utilizing local health data and data on the impact of existing SIFs in models for six outcomes: prevented human immunodeficiency virus transmission, Hepatitis C virus transmission, skin and soft-tissue infection, overdose mortality, and overdose-related medical care and increased medication-assisted treatment for opioid dependence.

resultsWe predict that for an annual cost of $1.8 million, a single SIF would generate $7.8 million in savings, preventing 3.7 HIV infections, 21 Hepatitis C infections, 374 days in the hospital for skin and soft-tissue infection, 5.9 overdose deaths, 108 overdose-related ambulance calls, 78 emergency room visits, and 27 hospitalizations, while bringing 121 additional people into treatment.

conclusionsWe conclude that a SIF would be both extremely cost-effective and a significant public health and economic benefit to Baltimore City.

Indexed as

BaltimoreCost-Benefit AnalysisDrug OverdoseHarm ReductionHepatitis CHeroin DependenceHIV InfectionsHumansModels, OrganizationalNeedle-Exchange ProgramsOpiate Substitution TreatmentPublic HealthBaltimore, MarylandCost-benefitCost-effectivenessHarm reductionHeroinOpiate overdosePeople who inject drugsSupervised consumption roomsSupervised injection facility

Identifiers

PMID28532488
PMCPMC5441005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.