Evidence map›Paper›PMID 28532484›Full record

ArticleJournal of health, population, and nutrition2017

Seasonal variations of vitamin D and its relation to lipid profile in Iranian children and adults.

Sakineh Nouri Saeidlou, Davoud Vahabzadeh, Fariba Babaei, Zakaria Vahabzadeh

Abstract readComparative Study
In one paragraph

Article in Journal of health, population, and nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. The Japanese Society of Hypertension Practical Consensus Guidelines for Seasonal Blood Pressure Management.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
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  8. Association of sun exposure and seasonality with vitamin D levels in Brazilian children and adolescents.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sakineh Nouri SaeidlouFood and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Davoud VahabzadehMaternal and Child Obesity Research Center (MCORC), Urmia University of Medical Sciences, Urmia, Iran. dvaha2003@yahoo.com.
Fariba BabaeiDeputy of Health, Urmia University of Medical Sciences, Urmia, Iran.
Zakaria VahabzadehLiver & Digestive Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D has a multitude of functional properties and acts like a hormone in the body. Its effect on the lipid profile is one of the proposed mechanisms for its relationship with many disorders during its deficiency. But, this relationship is still conflicting and debatable, so this study was conducted to determine the association between serum level of vitamin D and lipid profiles, including serum concentrations of cholesterol, triglyceride (TG), HDL, and LDL in healthy subjects.

methodsIn this cross-sectional study, 541 volunteers with age of 5-60 years from normal and healthy subjects were selected via random sampling. Demographics and history of daily or weekly sunlight exposures were recorded. Measuring vitamin D was done in two consecutive seasons: winter and summer. Ten milliliters of peripheral venous blood sample was withdrawn after an overnight fasting. Serum levels of 25(OH) D (25, hydroxy vitamin D3) were measured using the enzyme-linked immunosorbent assay (ELISA), and the Confirmatory test was done by high-performance liquid chromatography (HPLC).

resultsMean age in the total mixed population was 30.83 ± 14.02 years. Subjects were 50.5% male and 49.5% female. Mean 25(OH) D in the total population for winter and summer were 45.8 ± 24.26 ng/ml and 55.24 ± 37.47 ng/ml respectively. In the total population, 38.08% were vitamin D deficient. Comparing serum lipid levels in the summer and winter showed a significant difference for cholesterol, LDL, and HDL, but no significant effect was found for TG. Analysis for the comparison of lipid profiles between the two genders in winter showed that there were significant differences in all lipid profiles except for LDL, while such analysis for summer revealed significant difference just for TG. In multivariate analysis, there was a significant mean difference only for LDL in subgroups with vitamin D insufficiency and deficiency. There was no correlation between Vitamin D and lipid profiles.

conclusionsVitamin D is different between the two seasons regardless of gender variations. Its status showed some significant relationship with some lipid profiles (cholesterol, LDL, and HDL) during the two seasons. There were different results among winter and summer based on the gender.

Indexed as

AdolescentAdultBiomarkersCalcifediolChildChild, PreschoolCholesterolCross-Sectional StudiesFemaleHumansHypercholesterolemiaIranMaleMiddle AgedNutrition SurveysPrevalenceBiomarkersCalcifediolCholesterolAdultChildIranLipid profileVitamin D

Identifiers

PMID28532484
PMCPMC5441060

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.