Evidence map›Paper›PMID 28532423›Full record

ReviewJournal of translational medicine2017

The various aspects of genetic and epigenetic toxicology: testing methods and clinical applications.

Ning Ren, Manar Atyah, Wan-Yong Chen, Chen-Hao Zhou

Open access · goldAbstract readReview
In one paragraph

Review in Journal of translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. EccDNA-Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. The Toxicological Assessment ofNanomaterials (Basel, Switzerland) · 2023
    Article
  16. Review
  17. Dynamic changes of DNA methylation induced by benzo(a)pyrene in cancer.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2023
    Review
  18. Article
  19. Article
  20. Bioactive limonoids fromCurrent research in toxicology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ning RenLiver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China. ren.ning@zs-hospital.sh.cn.
Manar AtyahLiver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Wan-Yong ChenLiver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Chen-Hao ZhouLiver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Sun Yat-sen University · CNMinistry of Education of the People's Republic of China · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genotoxicity refers to the ability of harmful substances to damage genetic information in cells. Being exposed to chemical and biological agents can result in genomic instabilities and/or epigenetic alterations, which translate into a variety of diseases, cancer included. This concise review discusses, from both a genetic and epigenetic point of view, the current detection methods of different agents' genotoxicity, along with their basic and clinical relation to human cancer, chemotherapy, germ cells and stem cells.

Indexed as

Epigenesis, GeneticAnimalsComet AssayGerm CellsHumansNeoplasmsStem CellsToxicologyComet assayEpigeneticsGenetic toxicologyGenotoxicityGerm cellsIn-vivo testingStem cellsThe Ames assay

Identifiers

PMID28532423
PMCPMC5440915
OpenAlexW2619071941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.