Evidence map›Paper›PMID 28532409›Full record

ArticleBMC musculoskeletal disorders2017

Variation in Prosthetic Joint Infection and treatment strategies during 4.5 years of follow-up after primary joint arthroplasty using administrative data of 41397 patients across Australian, European and United States hospitals.

Perla J Marang-van de Mheen, Ellie Bragan Turner, Susan Liew, Nora Mutalima, Ton Tran, Sten Rasmussen, Rob G H H Nelissen, Andrew Gordon

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC musculoskeletal disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. The application of antibiotic-loaded bone cement in preventing periprosthetic joint infection: an umbrella review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
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  9. Outcome Predictors ofOpen forum infectious diseases · 2025
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  10. Periprosthetic joint infections - a scoping review.Innovative surgical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Perla J Marang-van de MheenDepartment of Medical Decision Making, Leiden University Medical Center, J10-S, PO Box 9600, 2300 RC, Leiden, The Netherlands. p.j.marang@lumc.nl.
Ellie Bragan TurnerDr Foster Ltd, London, UK.
Susan LiewDepartment of Orthopaedic Surgery, Alfred Hospital, Melbourne, Australia.
Nora MutalimaDepartment of Orthopaedic Surgery, Monash Health, Dandenong, Australia.
Ton TranDepartment of Orthopaedic Surgery, Monash Health, Dandenong, Australia.
Sten RasmussenOrthopaedic Surgery Research Unit, Aalborg University Hospital, Aalborg, Denmark.
Rob G H H NelissenDepartment of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Andrew GordonDepartment of Orthopaedic Surgery, Sheffield Teaching Hospitals NHS trust, Sheffield, UK.
Dandenong Hospital · AULeiden University Medical Center · NLAalborg University · DKFoster and Partners (United Kingdom) · GBSheffield Teaching Hospitals NHS Foundation Trust · GBThe Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo identify best practices and quality improvement initiatives, we aimed to assess whether the incidence of Periprosthetic Joint Infection (PJI) and treatment strategies differed across patients treated in Australian, European and United States (US) hospitals.

methodsRoutinely collected administrative data for 41397 patients undergoing a primary total hip or knee arthroplasty between July 2007-December 2010 across 22 hospitals were included. Patients were followed for 2 years looking for PJI occurrence, defined as early (within 4 weeks) and late PJI, and surgical treatment during 2.5 years after PJI diagnosis. Logistic and Poisson regression models were used to test for differences in PJI occurrence and treatment strategies across the three geographical regions, adjusted for age, sex, joint and Elixhauser comorbidity groups.

resultsPJI occurrence varied from 1.4% in European to 1.7% in Australian patients, which were significantly higher than US patients after adjustment for patient characteristics (OR 1.24 [1.01-1.52] and 1.40 [1.03-1.91] respectively). Early PJIs varied between 0.3% in European to 0.6% in Australian patients, but adjusted rates were similar. Revision following PJI was significantly lower in Australian than in US patients (OR 0.46 [0.25-0.86]) as were the total number of revisions (RR 0.51 [0.36-0.71]) and number of surgical procedures (RR 0.60 [0.44-0.81]) used to treat PJI.

conclusionThe overall PJI rate was significantly higher in Australian patients, but fewer procedures were needed to treat these PJIs. Future research should reveal whether this reflects PJIs caught earlier or less severe when diagnosed, and whether this is associated with the longer length of stay after primary arthroplasty in Australian hospitals.

Indexed as

InternationalityLength of StayAgedArthroplasty, Replacement, HipArthroplasty, Replacement, KneeAustraliaEuropeFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient AdmissionProsthesis-Related InfectionsRetrospective StudiesStatistics as TopicInternational variationPeriprosthetic Joint InfectionTotal joint replacementTreatment strategies

Identifiers

PMID28532409
PMCPMC5441102
OpenAlexW2618231508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.