ArticleBMC ophthalmology2017
Diagnostic performance of isolated-check visual evoked potential versus retinal ganglion cell-inner plexiform layer analysis in early primary open-angle glaucoma.
Article in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of isolated-check visual evoked potentials for glaucoma: a systematic review and meta-analysis.BMC ophthalmology · 2025Pooled it
- Glaucoma Classification Through SSVEP-Derived ON- and OFF-Pathway Features.Translational vision science & technology · 2026Article
- Utility of isolated-check visual evoked potential technique in dysthyroid optic neuropathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Diagnostic Capability of Isolated-Check Visual Evoked Potential for Early to Moderate Primary Open-Angle Glaucoma.Life (Basel, Switzerland) · 2023Article
- Diagnostic Accuracy of Imaging Devices in Glaucoma: An Updated Meta-Analysis.Medical journal of the Islamic Republic of Iran · 2023Article
- Preferential Loss of Contrast Decrement Responses in Human Glaucoma.Investigative ophthalmology & visual science · 2022Article
- Isolated-check visual evoked potential: a more sensitive tool to detect traumatic optic neuropathy after orbital fracture.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Applications of the isolated-check visual evoked potential in primary open angle glaucoma with or without high myopia.International journal of ophthalmology · 2021Article
- Discovery and clinical translation of novel glaucoma biomarkers.Progress in retinal and eye research · 2021Review
- Article
- Normal tension glaucoma: from the brain to the eye or the inverse?Neural regeneration research · 2019Review
- Applications of Isolated-Check Visual Evoked Potential in Early Stage of Open-Angle Glaucoma Patients.Chinese medical journal · 2018Article
- Treatment of glaucomatous optic nerve damage using ginsenoside Rg1 mediated by ultrasound targeted microbubble destruction.Experimental and therapeutic medicine · 2018Article
- Visual evoked potential in the early diagnosis of glaucoma. Literature review.Romanian journal of ophthalmologyReview
- The neuroprotective role of citicoline treatment in glaucoma - 6 months results of a prospective therapeutic trial.Romanian journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to compare the diagnostic performance of isolated-check visual evoked potential (icVEP) with that of retinal ganglion cell-inner plexiform layer (GCILP) analysis using optical coherence tomography (OCT).
methodsA total of 45 patients were enrolled: 25 patients with open-angle glaucoma and 20 healthy patients. All patients underwent a complete ophthalmological examination. Moreover, the OCT examination was used to analyze the structures of the GCIPL. The icVEP technique was used to detect the transmission function of the magnocellular pathway, which is mainly managed by the retinal ganglion cells. The quantitative and qualitative comparisons between the diagnostic power of GCIPL analysis and that of icVEP were performed. The areas under the receiver operating characteristic curves (AUC) of GCIPL analysis and icVEP were compared using the Clarke-Pearson method. The sensitivity and specificity of the two techniques were analyzed and compared using the McNemar test.
resultsWith the quantitative comparison, the AUC of icVEP (AUC = 0.892) was higher than that of GCIPL analysis (AUC = 0.814). However, there was no statistical significance between the AUCs of icVEP and GCIPL (P > 0.05). With the qualitative comparison, the sensitivity of icVEP was 80%, and its specificity was 90%. The sensitivity of GCIPL analysis was 72%, and its specificity was 85%. There was no significant difference between the sensitivitiesor specificities of icVEP and GCIPL analysis (P > 0.05). Moreover, 30 (66.67%) eyeshad similar resultsbetween icVEP and GCIPL analysis, and 15 (33.33%) eyes had different results (7 eyes had abnormal results with GCIPL analysisbut normal results with icVEP, and8 eyes had normal results with GCIPL analysisbut abnormal results with icVEP).
conclusionsThe diagnostic power of icVEP was close to that of GCIPL analysis whether the comparison was based on the qualitative or quantitative data.
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