Evidence map›Paper›PMID 28532358›Full record

ReviewAnnual review of vision science2016

Experience-Dependent Structural Plasticity in the Visual System.

Kalen P Berry, Elly Nedivi

Abstract readReview
In one paragraph

Review in Annual review of vision science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
  2. Article
  3. Critical period plasticity enables credit assignment.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Cortical Somatostatin Innervation Follows a Unique Experience-Independent Developmental Trajectory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. The epithelial NaCell reports · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kalen P BerryPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139; email: nedivi@mit.edu.
Elly NediviPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139; email: nedivi@mit.edu.

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
A Molecular Genetic Analysis of Cortical PlasticityR01EY011894 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NEDIVI, ELLY · 2003 to 2016
$5.2M
In vivo imaging of inhibitory circuit remodeling in mouse visual cortexR01EY025437 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NEDIVI, ELLY · 2015 to 2021
$2.5M
In Vivo Imaging of Neuronal Plasticity in Visual CortexR01EY017656 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NEDIVI, ELLY, SO, PETER T. · 2008 to 2014
$2.5M
NEI NIH HHS R01 EY011894NEI NIH HHS R01 EY017656NEI NIH HHS R01 EY025437NIGMS NIH HHS T32 GM007287
6 · The paper itself

Abstract

During development, the environment exerts a profound influence on the wiring of brain circuits. Due to the limited resolution of studies in fixed tissue, this experience-dependent structural plasticity was once thought to be restricted to a specific developmental time window. The recent introduction of two-photon microscopy for in vivo imaging has opened the door to repeated monitoring of individual neurons and the study of structural plasticity mechanisms at a very fine scale. In this review, we focus on recent work showing that synaptic structural rearrangements are a key mechanism mediating neural circuit adaptation and behavioral plasticity in the adult brain. We examine this work in the context of classic studies in the visual systems of model organisms, which have laid much of the groundwork for our understanding of activity-dependent synaptic remodeling and its role in brain plasticity.

Indexed as

AnimalsHumansNeuronal PlasticitySynapsesVisual CortexVisual PathwaysVisual Perceptioncircuit remodelingretinogeniculate afferentsretinotectal systemstructural plasticitysynapse dynamicsvisual cortex

Identifiers

PMID28532358
PMCPMC7047654

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.