Evidence map›Paper›PMID 28532347›Full record

ArticleAnnual review of vision science2016

Strabismus and the Oculomotor System: Insights from Macaque Models.

Vallabh E Das

Abstract read
In one paragraph

Article in Annual review of vision science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Neural Control of Vergence and Ocular Accommodation.Annual review of vision science · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Distinct context- and content-dependent population codes in superior colliculus during sensation and action.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Dichoptic visual field mapping of suppression in exotropia with homonymous hemianopia.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2021
    Article
  15. Article
  16. Article
  17. Interocular Suppression in Primary Visual Cortex in Strabismus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Vallabh E DasCollege of Optometry, University of Houston, Houston, Texas 77204; email: vdas@central.uh.edu.

Funding

Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI VALLABH E DAS · 1988 to 2026
$16.4M
Binocular Coordination of Eye MovementsR01EY026568 · NEI · UNIVERSITY OF HOUSTON · PI VALLABH E DAS · 2016 to 2026
$5.0M
BINOCULAR COORDINATION OF EYE MOVEMENTSR01EY015312 · NEI · UNIVERSITY OF HOUSTON · PI DAS, VALLABH E · 2004 to 2015
$3.3M
Neural Adaptation to Strabismus SurgeryR01EY022723 · NEI · UNIVERSITY OF HOUSTON · PI DAS, VALLABH E · 2012 to 2015
$1.3M
NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY015312NEI NIH HHS R01 EY022723NEI NIH HHS R01 EY026568
6 · The paper itself

Abstract

Disrupting binocular vision in infancy leads to strabismus and oftentimes to a variety of associated visual sensory deficits and oculomotor abnormalities. Investigation of this disorder has been aided by the development of various animal models, each of which has advantages and disadvantages. In comparison to studies of binocular visual responses in cortical structures, investigations of neural oculomotor structures that mediate the misalignment and abnormalities of eye movements have been more recent, and these studies have shown that different brain areas are intimately involved in driving several aspects of the strabismic condition, including horizontal misalignment, dissociated deviations, A and V patterns of strabismus, disconjugate eye movements, nystagmus, and fixation switch. The responses of cells in visual and oculomotor areas that potentially drive the sensory deficits and also eye alignment and eye movement abnormalities follow a general theme of disrupted calibration, lower sensitivity, and poorer specificity compared with the normally developed visual oculomotor system.

Indexed as

AnimalsBrainDisease Models, AnimalEye MovementsMacaca mulattaOculomotor MusclesParesisStrabismusVision, Binocularanimal modeleye movementsneural substratenonhuman primatestrabismusstrabismus treatment

Identifiers

PMID28532347
PMCPMC5443124

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.