ReviewPlant signaling & behavior2017
Heterotrimeric G-protein regulatory circuits in plants: Conserved and novel mechanisms.
Review in Plant signaling & behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 15 citations in OpenAlex.
- Research Advances in Heterotrimeric G-Protein α Subunits and Uncanonical G-Protein Coupled Receptors in Plants.International journal of molecular sciences · 2021Review
- Heterotrimeric G-Protein Interactions Are Conserved Despite Regulatory Element Loss in Some Plants.Plant physiology · 2020Article
- Cellular Organization and Regulation of Plant Glycerolipid Metabolism.Plant & cell physiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ARTICLE ADDENDUM Efficient activation and deactivation of Gα protein is critical for the regulation of heterotrimeric G-protein mediated signaling pathways. While the core G-protein components and their activation/deactivation chemistries are broadly conserved throughout the eukaryotic evolution, their regulatory mechanisms seem to have been rewired in plants to meet specific needs. Plants such as Arabidopsis, which have a limited number of G-protein components and their regulators, offer a unique opportunity to dissect the mechanistic details of distinct signaling pathways. We have recently established an interaction between the regulator of G-protein signaling 1 (RGS1) and phospholipase Dα1 (PLDα1); 2 of the GTPase activity accelerating proteins (GAPs) of the Arabidopsis Gα protein, GPA1. We now show that phosphatidic acid (PA), a key product of PLDα1 activity, can bind with and modulate the GAP activity of RGS1, uncovering a molecular link between lipid and G-protein signaling and its role in providing the specificity of response regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.