ReviewInternational journal of stem cells2017
Methods of Isolation and Characterization of Stem Cells from Different Regions of Oral Cavity Using Markers: A Systematic Review.
Review in International journal of stem cells, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Autologous dental pulp mesenchymal stem cells for inferior third molar post-extraction socket healing: A split-mouth randomised clinical trial.Medicina oral, patologia oral y cirugia bucal · 2018Trial
- Characteristics of the Stem Cell Intellectual Property Rights and Patent Status: Focusing on Papers and Clinical Trials.Development & reproduction · 2026Article
- MiR-146a participates in regulating the progression of periodontitis through the Wnt/β-catenin signaling pathway.PloS one · 2025Article
- A Review of Stem Cell Attributes Derived from the Oral Cavity.International dental journal · 2024Review
- Protective role of stem cells in POI: Current status and mechanism of action, a review article.Heliyon · 2024Review
- Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer.Frontiers in cell and developmental biology · 2023Article
- Knowledge, attitude, and practice survey on the use of stamp technique for the management of Class I caries in molars among undergraduate students in dental schools.Journal of advanced pharmaceutical technology & research · 2022Article
- Awareness on the management strategy of stitch abscess among dental students.Journal of advanced pharmaceutical technology & research · 2022Article
- Need for practice management in undergraduate dental program - A cross sectional survey among the dentists.Journal of advanced pharmaceutical technology & research · 2022Article
- Knowledge and awareness of forensic dentistry course among undergraduates.Journal of advanced pharmaceutical technology & research · 2022Article
- Current status of usage of ivermectin in the management of COVID.Journal of advanced pharmaceutical technology & research · 2022Article
- Practice management in undergraduate dental program: The need among dental students.Journal of advanced pharmaceutical technology & research · 2022Article
- Evaluation of accuracy and time taken to make an open tray implant impressions with two techniques.Journal of advanced pharmaceutical technology & research · 2022Article
- Presence of impacted supernumerary teeth in the Indian population.Journal of advanced pharmaceutical technology & research · 2022Article
- Awareness on resonance frequency analysis in dental implantology among dental practitioners and dental students.Journal of advanced pharmaceutical technology & research · 2022Article
- Awareness on current status of usage of ritonavir in the management of covid among dental students.Journal of advanced pharmaceutical technology & research · 2022Article
- Knowledge, awareness, and practice survey on conventional radiographic methods and processing among dental students.Journal of advanced pharmaceutical technology & research · 2022Article
- Expectation of treatment outcomes in complete denture wearers.Journal of advanced pharmaceutical technology & research · 2022Article
- A Narrative Review: Gingival Stem Cells as a Limitless Reservoir for Regenerative Medicine.International journal of molecular sciences · 2022Review
- Chronic metabolic and induced stress impacts mesenchymal stromal cell differentiation and modulation of dental originSaudi journal of biological sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Periodontitis is a destructive inflammatory disorder of the periodontium caused by the destruction of periodontal tissues namely the PDL, cementum, alveolar bone, and gingiva. Once these tissues are lost, the foremost goal of periodontal therapy is to regenerate the diseased tissues if possible to their original form, architecture, and function. Various regenerative procedures were employed and still a gap was found in achieving the goal. As stem cells are characterized by their ability to self-renew and differentiate to produce specialized cells, there could be a possibility of using them for regenerative therapy. Recently, dental tissues such as the PDL, the dental pulp and the tooth follicle have been recognized as readily available sources of adult stem cells. Aim: The aim was to identify the various sources and methodologies in isolation of stem cells from human oral cavity and its differentiation into various lineages using markers. Materials and Methods: The electronic databases PUBMED, GOOGLE SCHOLAR, SCIENCE DIRECT, COCHRANE LIBRARY along with a complimentary manual search of all periodontics journal till the year 2016. Thirteen articles were selected on the basis of the inclusion criteria. Isolation of stem cells from oral cavity through various methods has been evaluated and similarly characterization to different lineages were tabulated as variables of interest. They included human in-vitro and ex-vivo studies. Results: The results showed that PDLSC's and pulpal stem cells are the most common source from where stem cells were isolated. Each source has used different methodology in isolating the stem cells and it was found that STRO-1 was the commonly used marker in all the studies mentioned. Conclusions: The studies showed that there is no standard protocol existed in isolating the stem cells from different sources of oral cavity. Moreover, there was no standard marker or methodology used in characterization.
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Registered trials
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