ArticleAmerican journal of hypertension2017
Current Trends of Hypertension Treatment in the United States.
Article in American journal of hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genome-Wide Meta-Analysis of Blood Pressure Response to βJournal of the American Heart Association · 2019Pooled it
- Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema.The American journal of emergency medicine · 2023Trial
- Prescription Trends of Initial Antihypertensive Medications Among Presumed Treatment-Naïve Individuals in Korea: A Retrospective Analysis.Journal of Korean medical science · 2026Article
- 5-Hydroxytryptamine may be a viable treatment option for hypertension resistant to diuretic treatment.American journal of physiology. Heart and circulatory physiology · 2025Article
- Molecular mechanisms of thiazide-like diuretics-mediated inhibition of the human Na-Cl cotransporter.Nature communications · 2025Article
- Hydrochlorothiazide Is America's Most Popular Thiazide, But Should It Be?Journal of the American Heart Association · 2025Article
- Estimating the economic impact of blister-packaging on medication adherence and health care costs for a Medicare Advantage health plan.Journal of managed care & specialty pharmacy · 2024Article
- Cumulative incidence and risk factors of myocardial infarction during 20 years of follow-up: comparing two cohorts of middle-aged men born 30 years apart.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Use and Cost Patterns of Antihypertensive Medications in the United States From 1996 to 2021.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Trends in Initial Antihypertensive Medication Prescribing Among >2.8 Million Veterans Newly Diagnosed With Hypertension, 2000 to 2019.Journal of the American Heart Association · 2024Article
- Associations of actigraph sleep characteristics with blood pressure among older adults.Sleep health · 2024Article
- Dihydropyridine Calcium Channel Blockers and Kidney Outcomes.Journal of general internal medicine · 2024Article
- The impact of dietary supplements on blood pressure in older adults: A network meta-analysis of randomized controlled trials.Heliyon · 2024Article
- Patient-Reported Reasons for Antihypertensive Medication Change: A Quantitative Study Using Social Media.Drug safety · 2024Article
- Improving Adherence and Reducing Health Care Costs Through Blister-Packaging: An Economic Model for a Commercially Insured Health Plan.ClinicoEconomics and outcomes research : CEOR · 2024Article
- Targeting lymphatic function in cardiovascular-kidney-metabolic syndrome: preclinical methods to analyze lymphatic function and therapeutic opportunities.Frontiers in cardiovascular medicine · 2024Review
- Initial Antihypertensive Regimens in Newly Treated Patients: Real World Evidence From the OneFlorida+ Clinical Research Network.Journal of the American Heart Association · 2023Article
- Pairwise comparison of hydrochlorothiazide and chlorthalidone responses among hypertensive patients.Clinical and translational science · 2022Article
- Thiazide Diuretics and Fracture Risk: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.JBMR plus · 2022Article
- Discontinuation of low-dose thiazide treatment in hypertensive patients associated with improvement in glycemic profile.Internal and emergency medicine · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundTo examine current patterns of hypertension (HTN) treatment in the United States, including blood pressure (BP) control, prevalence of different antihypertensive agents, and variations in treatment associated with patient and physician characteristics.
methodsWe used data from the National Disease and Therapeutic Index (NDTI), a nationally representative physician survey produced by QuintilesIMS. We selected patients with a diagnosis of HTN and identified those prescribed antihypertensive therapies. We analyzed the type of antihypertensive agents prescribed. Extent of BP control, and associated patient and physician characteristics. We calculated 95% confidence intervals that accounted for the multistage NDTI sampling design.
resultsAmong those treated for HTN in 2014, BP control varied: systolic BP (SBP) ≥160 (15%) vs. SBP 150-159 (9%) vs. SBP 140-149 (19%) vs. SBP 130-139 (26%) vs. SBP <130 (32%). Of those treated for HTN, 29% used of angiotensin-converting enzyme inhibitors (ACEIs); 24%, thiazide-like diuretics; 22%, angiotensin receptor blockers (ARBs), 21%, calcium-channel blockers (CCBs); and 19% beta-blockers. Newer drugs had very limited uptake; no drugs approved after 2002 were used in more than 5% of patients. Selection of agents varied only modestly by patient and physician characteristics.
conclusionsThe treatment of HTN in 2014 predominantly involved older medications in 5 major classes of drugs: ACEIs, thiazide diuretics, ARBs, CCBs, and beta-blockers. Selection of antihypertensive agents showed limited variation by age, gender, race, and insurance type. Although 58% of treated patients had SBP <140, 24% had poorly controlled HTN with SBP ≥150, indicating the need for improved treatment.
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