Evidence map›Paper›PMID 28531166›Full record

ArticleNutrients2017

(-)-Epiafzelechin Protects against Ovariectomy-induced Bone Loss in Adult Mice and Modulate Osteoblastic and Osteoclastic Functions In Vitro.

Ka-Chun Wong, Sisi Cao, Xiaoli Dong, Man-Chun Law, Tak-Hang Chan, Man-Sau Wong

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Ka-Chun WongState Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen 518057, China. aguesses@yahoo.com.hk.
Sisi CaoState Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen 518057, China. sissi.cao@connect.polyu.hk.
Xiaoli DongDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China. xiaoli.dong@polyu.edu.hk.
Man-Chun LawDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China. manchunlaw@hotmail.com.
Tak-Hang ChanDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China. tak-hang.chan@polyu.edu.hk.
Man-Sau WongState Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen 518057, China. man-sau.wong@polyu.edu.hk.
Hong Kong Polytechnic University · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was designed to characterize the bone protective effects of (-)-

Indexed as

AnimalsBiomarkersBone DensityCalciumCatechinFemaleMiceMice, Inbred C57BLMolecular StructureOsteoblastsOsteocalcinOsteoclastsOsteoporosisOvariectomyRAW 264.7 CellsRNA, MessengerBiomarkersCalciumCatechinepiafzelechinOsteocalcinRNA, Messenger(−)-epiafzelechinflavan-3-olosteoclastogenesisosteogenesisovariectomisedtrabecular bone

Identifiers

PMID28531166
PMCPMC5452259
OpenAlexW2619941415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.