ArticleChildren (Basel, Switzerland)2017
Genetic Testing among Children in a Complex Care Program.
Article in Children (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Is next generation sequencing for the diagnosis of rare diseases worth its cost? A user-based approach to valuation.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Episignature leads to diagnosis and reclassification of DYRK1A variant in a child with syndromic neurodevelopmental disorder: a case report.Frontiers in genetics · 2026Article
- An integrated clinical approach to children at genetic risk for neurodevelopmental and psychiatric conditions: interdisciplinary collaboration and research infrastructure.Journal of neurodevelopmental disorders · 2024Article
- Impact of deep phenotyping: high diagnostic yield in a diverse pediatric population of 172 patients through clinical whole-genome sequencing at a single center.Frontiers in genetics · 2024Article
- Pharmacogenetic profiling via genome sequencing in children with medical complexity.Pediatric research · 2023Article
- Contemporary aetiologies of medical complexity in children: a cohort study.Archives of disease in childhood · 2023Article
- Article
- Cost-effectiveness of genome-wide sequencing for unexplained developmental disabilities and multiple congenital anomalies.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- (Un)standardized testing: the diagnostic odyssey of children with rare genetic disorders in Alberta, Canada.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- Clinical utility of genomic sequencing: a measurement toolkit.NPJ genomic medicine · 2020Review
- Ethical Considerations on Pediatric Genetic Testing Results in Electronic Health Records.Applied clinical informatics · 2020Article
- Genome Sequencing as a Diagnostic Test in Children With Unexplained Medical Complexity.JAMA network open · 2020Article
- Genome-Wide Sequencing for Unexplained Developmental Disabilities or Multiple Congenital Anomalies: A Health Technology Assessment.Ontario health technology assessment series · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little is known about the pattern of genetic testing and frequency of genetic diagnoses among children enrolled in structured complex care programs (CCPs). Such information may inform the suitability of emerging genome diagnostics for this population. The objectives were to describe the proportion of children with undiagnosed genetic conditions despite genetic testing and measure the testing period, types and costs of genetic tests used. A retrospective analysis of 420 children enrolled in Toronto's Hospital for Sick Children's CCP from January 2010 until June 2014 was conducted. Among those who underwent genetic testing (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.