Evidence map›Paper›PMID 28531122›Full record

ArticleMolecules (Basel, Switzerland)2017

Microwave-Assisted Synthesis of Imidazo[4,5-f][1,10]phenanthroline Derivatives as Apoptosis Inducers in Chemotherapy by Stabilizing Bcl-2 G-quadruplex DNA.

Li Li, Jie-Qiong Cao, Hui-Min Liu, Qiong Wu, Qiu-Hui Pan, Zhi-Ping Zeng, Yu-Tao Lan, Yu-Mei Li, Wen-Jie Mei, Xi-Cheng Wang and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Li LiThe First Affiliation Hospital, Guangdong Pharmaceutical University, Guangzhou 510006, China. lili7sy@163.com.
Jie-Qiong CaoDepartment of Chemistry, Jinan University, Guangzhou 510006, China. caojieqiong93@163.com.
Hui-Min LiuThe First Affiliation Hospital, Guangdong Pharmaceutical University, Guangzhou 510006, China. 13570250612@163.com.
Qiong WuDepartment of Chemistry, Jinan University, Guangzhou 510006, China. wuqiongniu.1113@163.com.
Qiu-Hui PanDepartment of Laboratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China. panqiuhui@263.net.
Zhi-Ping ZengSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. 13086287838@163.com.
Yu-Tao LanSchool of Nursing, Guangdong Pharmaceutical University, Guangzhou 510006, China. lanyutao@gdpu.edu.cn.
Yu-Mei LiSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. 15975634468@163.com.
Wen-Jie MeiSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. wenjiemei@126.com.
Xi-Cheng WangThe First Affiliation Hospital, Guangdong Pharmaceutical University, Guangzhou 510006, China. 13902400598@126.com.
Wen-Jie ZhengDepartment of Chemistry, Jinan University, Guangzhou 510006, China. tzhwj@jnu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, a series of imidazo[4,5-

Indexed as

A549 CellsAntineoplastic AgentsApoptosisBiological TransportCell Line, TumorCell Membrane PermeabilityCell SurvivalGene ExpressionG-QuadruplexesHumansImidazolesMicrowavesMitochondriaNucleic Acid DenaturationPhenanthrolinesProtein Stability1H-imidazo(4,5-f)(1,10)phenanthrolineAntineoplastic AgentsBCL2 protein, humanImidazolesPhenanthrolinesProto-Oncogene Proteins c-bcl-2apoptosis inducersbcl-2 G-quadruplex DNAimidazo[4,5-f][1,10]phenanthroline derivativesmicrowave-assisted synthesis

Identifiers

PMID28531122
PMCPMC6154642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.