ArticleNature immunology2017
CD8αα intraepithelial lymphocytes arise from two main thymic precursors.
Article in Nature immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 117 citations in OpenAlex.
- PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation.The Journal of clinical investigation · 2018Trial
- T Cell Thoughts.Immunological reviews · 2026Review
- Analysis of Human Thymopoiesis Reveals Rapid Postnatal Remodeling of Thymocytes Within the First 3 Months of Life.European journal of immunology · 2026Article
- GPR15-GPR15L axis controls colon natural TCRαβ cells residency and enteroendocrine cell homeostasis to calibrate metabolism.Mucosal immunology · 2026Article
- Weak SLP-76/PLC-γ1 interaction fine-tunes T cell receptor signal strength to optimize T cell responsiveness.Nature communications · 2026Article
- Fine tuning of TCR signaling via CD8αβ and PD-1 and the fate of autoreactive thymocytes during negative selection.ImmunoHorizons · 2026Article
- Unbiased recording and identification of thymic cellular interactomes using synthetic Notch receptors.Nature communications · 2026Article
- Memory-biased CD8αα⁺ T cells show reduced abundance and phenotypic remodeling in SLE.Immunologic research · 2026Article
- Developmental hematopoiesis: innate programming of αβ T cells.Experimental hematology · 2026Review
- Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes.bioRxiv : the preprint server for biology · 2025Article
- An SSTR2-somatostatin chemotactic axis drives T cell progenitor homing to the intestines.Nature immunology · 2025Article
- Article
- Ligands for Intestinal Intraepithelial T Lymphocytes in Health and Disease.Pathogens (Basel, Switzerland) · 2025Review
- Heterogeneity of CD8αα intraepithelial lymphocytes is transcriptionally conserved between TCRαβ and TCRγδ cell lineages.Frontiers in immunology · 2025Article
- Dynamic Changes in the Intraepithelial Lymphocyte Numbers FollowingAnimals : an open access journal from MDPI · 2024Article
- The partitioning of TCR repertoires by thymic selection.The Journal of experimental medicine · 2024Review
- Article
- Adaptive immunity to retroelements promotes barrier integrity.bioRxiv : the preprint server for biology · 2024Article
- Characterization of novel CD8Cellular and molecular life sciences : CMLS · 2024Article
- NKT Cells and Other Innate T Cells: The Immune Cells That Do Not Follow the Rules.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
TCRαβ
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.