ArticleNature neuroscience2017
A cerebellum-like circuit in the auditory system cancels responses to self-generated sounds.
Article in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
65 citing papers in PubMed, 133 citations in OpenAlex.
- Listening to music while running alters ground reaction forces: a study of acute exposure to varying speed and loudness levels in young women and men.European journal of applied physiology · 2020Trial
- Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans.Science translational medicine · 2018Trial
- Motor Prediction Reduces Beta-Band Power and Enhances Cerebellar-Somatosensory Connectivity before Self-Touch to Enable Its Attenuation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Similarities betweeneNeuro · 2026Article
- Motor signals modulate cortical but not subcortical processing of self-initiated sounds.bioRxiv : the preprint server for biology · 2026Article
- Auditory Cortex Distinguishes between Spontaneous and Sound-Evoked Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Rethinking hierarchy: the auditory system as an integrated cortical-subcortical network.Nature reviews. Neuroscience · 2026Review
- Locomotion-induced neural activity independent of auditory feedback in the mouse inferior colliculus.iScience · 2026Article
- Rapid motor skill adjustment is associated with population-level modulation of cerebellar error signals.Nature neuroscience · 2026Article
- Cortical somatosensory responses evoked by orofacial skin stretch experimentally applied during speech movement planning in stuttering and nonstuttering adults.IBRO neuroscience reports · 2025Article
- Suppressing Sensation during Action across Species and Sensory Modalities: Predictive and Nonpredictive Mechanisms of Sensory Modulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- The dorsal/ventral subdivision of the hindbrain predates the tunicate/vertebrate split.bioRxiv : the preprint server for biology · 2025Article
- Article
- Impaired motor-to-sensory transformation mediates auditory hallucinations.PLoS biology · 2024Article
- Mixed Representations of Sound and Action in the Auditory Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Deep homologies in chordate caudal central nervous systems.bioRxiv : the preprint server for biology · 2024Article
- Learning within a sensory-motor circuit links action to expected outcome.bioRxiv : the preprint server for biology · 2024Article
- Calcium-Sensitive Subthreshold Oscillations and Electrical Coupling in Principal Cells of Mouse Dorsal Cochlear Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The dorsal cochlear nucleus (DCN) integrates auditory nerve input with a diverse array of sensory and motor signals processed in circuitry similar to that of the cerebellum. Yet how the DCN contributes to early auditory processing has been a longstanding puzzle. Using electrophysiological recordings in mice during licking behavior, we show that DCN neurons are largely unaffected by self-generated sounds while remaining sensitive to external acoustic stimuli. Recordings in deafened mice, together with neural activity manipulations, indicate that self-generated sounds are cancelled by non-auditory signals conveyed by mossy fibers. In addition, DCN neurons exhibit gradual reductions in their responses to acoustic stimuli that are temporally correlated with licking. Together, these findings suggest that DCN may act as an adaptive filter for cancelling self-generated sounds. Adaptive filtering has been established previously for cerebellum-like sensory structures in fish, suggesting a conserved function for such structures across vertebrates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.